In this work, we present the design of a superconducting, microwave quantum state router which can realize all-to-all couplings among four quantum modules. Each module consists of a single transmon, readout mode, and communication mode coupled to the
router. The router design centers on a parametrically driven, Josephson-junction based three-wave mixing element which generates photon exchange among the modules communication modes. We first demonstrate SWAP operations among the four communication modes, with an average full-SWAP time of 760 ns and average inter-module gate fidelity of 0.97, limited by our modes coherences. We also demonstrate photon transfer and pairwise entanglement between the modules qubits, and parallel operation of simultaneous SWAP gates across the router. These results can readily be extended to faster and higher fidelity router operations, as well as scaled to support larger networks of quantum modules.
Registration of 3D anatomic structures to their 2D dual fluoroscopic X-ray images is a widely used motion tracking technique. However, deep learning implementation is often impeded by a paucity of medical images and ground truths. In this study, we p
roposed a transfer learning strategy for 3D-to-2D registration using deep neural networks trained from an artificial dataset. Digitally reconstructed radiographs (DRRs) and radiographic skull landmarks were automatically created from craniocervical CT data of a female subject. They were used to train a residual network (ResNet) for landmark detection and a cycle generative adversarial network (GAN) to eliminate the style difference between DRRs and actual X-rays. Landmarks on the X-rays experiencing GAN style translation were detected by the ResNet, and were used in triangulation optimization for 3D-to-2D registration of the skull in actual dual-fluoroscope images (with a non-orthogonal setup, point X-ray sources, image distortions, and partially captured skull regions). The registration accuracy was evaluated in multiple scenarios of craniocervical motions. In walking, learning-based registration for the skull had angular/position errors of 3.9 +- 2.1 deg / 4.6 +- 2.2 mm. However, the accuracy was lower during functional neck activity, due to overly small skull regions imaged on the dual fluoroscopic images at end-range positions. The methodology to strategically augment artificial training data can tackle the complicated skull registration scenario, and has potentials to extend to widespread registration scenarios.
COVID-19 has caused lasting damage to almost every domain in public health, society, and economy. To monitor the pandemic trend, existing studies rely on the aggregation of traditional statistical models and epidemic spread theory. In other words, hi
storical statistics of COVID-19, as well as the population mobility data, become the essential knowledge for monitoring the pandemic trend. However, these solutions can barely provide precise prediction and satisfactory explanations on the long-term disease surveillance while the ubiquitous social media resources can be the key enabler for solving this problem. For example, serious discussions may occur on social media before and after some breaking events take place. These events, such as marathon and parade, may impact the spread of the virus. To take advantage of the social media data, we propose a novel framework, Social Media enhAnced pandemic suRveillance Technique (SMART), which is composed of two modules: (i) information extraction module to construct heterogeneous knowledge graphs based on the extracted events and relationships among them; (ii) time series prediction module to provide both short-term and long-term forecasts of the confirmed cases and fatality at the state-level in the United States and to discover risk factors for COVID-19 interventions. Extensive experiments show that our method largely outperforms the state-of-the-art baselines by 7.3% and 7.4% in confirmed case/fatality prediction, respectively.
The clinical named entity recognition (CNER) task seeks to locate and classify clinical terminologies into predefined categories, such as diagnostic procedure, disease disorder, severity, medication, medication dosage, and sign symptom. CNER facilita
tes the study of side-effect on medications including identification of novel phenomena and human-focused information extraction. Existing approaches in extracting the entities of interests focus on using static word embeddings to represent each word. However, one word can have different interpretations that depend on the context of the sentences. Evidently, static word embeddings are insufficient to integrate the diverse interpretation of a word. To overcome this challenge, the technique of contextualized word embedding has been introduced to better capture the semantic meaning of each word based on its context. Two of these language models, ELMo and Flair, have been widely used in the field of Natural Language Processing to generate the contextualized word embeddings on domain-generic documents. However, these embeddings are usually too general to capture the proximity among vocabularies of specific domains. To facilitate various downstream applications using clinical case reports (CCRs), we pre-train two deep contextualized language models, Clinical Embeddings from Language Model (C-ELMo) and Clinical Contextual String Embeddings (C-Flair) using the clinical-related corpus from the PubMed Central. Explicit experiments show that our models gain dramatic improvements compared to both static word embeddings and domain-generic language models.
In the practical continuous-variable quantum key distribution (CV-QKD) system, the postprocessing process, particularly the error correction part, significantly impacts the system performance. Multi-edge type low-density parity-check (MET-LDPC) codes
are suitable for CV-QKD systems because of their Shannon-limit-approaching performance at a low signal-to-noise ratio (SNR). However, the process of designing a low-rate MET-LDPC code with good performance is extremely complicated. Thus, we introduce Raptor-like LDPC (RL-LDPC) codes into the CV-QKD system, exhibiting both the rate compatible property of the Raptor code and capacity-approaching performance of MET-LDPC codes. Moreover, this technique can significantly reduce the cost of constructing a new matrix. We design the RL-LDPC matrix with a code rate of 0.02 and easily and effectively adjust this rate from 0.016 to 0.034. Simulation results show that we can achieve more than 98% reconciliation efficiency in a range of code rate variation using only one RL-LDPC code that can support high-speed decoding with an SNR less than -16.45 dB. This code allows the system to maintain a high key extraction rate under various SNRs, paving the way for practical applications of CV-QKD systems with different transmission distances.
Recent advances have shown that symmetry, a structural prior that most objects exhibit, can support a variety of single-view 3D understanding tasks. However, detecting 3D symmetry from an image remains a challenging task. Previous works either assume
that the symmetry is given or detect the symmetry with a heuristic-based method. In this paper, we present NeRD, a Neural 3D Reflection Symmetry Detector, which combines the strength of learning-based recognition and geometry-based reconstruction to accurately recover the normal direction of objects mirror planes. Specifically, we first enumerate the symmetry planes with a coarse-to-fine strategy and then find the best ones by building 3D cost volumes to examine the intra-image pixel correspondence from the symmetry. Our experiments show that the symmetry planes detected with our method are significantly more accurate than the planes from direct CNN regression on both synthetic and real-world datasets. We also demonstrate that the detected symmetry can be used to improve the performance of downstream tasks such as pose estimation and depth map regression. The code of this paper has been made public at https://github.com/zhou13/nerd.
Clinical case reports are written descriptions of the unique aspects of a particular clinical case, playing an essential role in sharing clinical experiences about atypical disease phenotypes and new therapies. However, to our knowledge, there has be
en no attempt to develop an end-to-end system to annotate, index, or otherwise curate these reports. In this paper, we propose a novel computational resource platform, CREATe, for extracting, indexing, and querying the contents of clinical case reports. CREATe fosters an environment of sustainable resource support and discovery, enabling researchers to overcome the challenges of information science. An online video of the demonstration can be viewed at https://youtu.be/Q8owBQYTjDc.
There has been a steady need in the medical community to precisely extract the temporal relations between clinical events. In particular, temporal information can facilitate a variety of downstream applications such as case report retrieval and medic
al question answering. Existing methods either require expensive feature engineering or are incapable of modeling the global relational dependencies among the events. In this paper, we propose a novel method, Clinical Temporal ReLation Exaction with Probabilistic Soft Logic Regularization and Global Inference (CTRL-PG) to tackle the problem at the document level. Extensive experiments on two benchmark datasets, I2B2-2012 and TB-Dense, demonstrate that CTRL-PG significantly outperforms baseline methods for temporal relation extraction.
We present HoliCity, a city-scale 3D dataset with rich structural information. Currently, this dataset has 6,300 real-world panoramas of resolution $13312 times 6656$ that are accurately aligned with the CAD model of downtown London with an area of m
ore than 20 km$^2$, in which the median reprojection error of the alignment of an average image is less than half a degree. This dataset aims to be an all-in-one data platform for research of learning abstracted high-level holistic 3D structures that can be derived from city CAD models, e.g., corners, lines, wireframes, planes, and cuboids, with the ultimate goal of supporting real-world applications including city-scale reconstruction, localization, mapping, and augmented reality. The accurate alignment of the 3D CAD models and panoramas also benefits low-level 3D vision tasks such as surface normal estimation, as the surface normal extracted from previous LiDAR-based datasets is often noisy. We conduct experiments to demonstrate the applications of HoliCity, such as predicting surface segmentation, normal maps, depth maps, and vanishing points, as well as test the generalizability of methods trained on HoliCity and other related datasets. HoliCity is available at https://holicity.io.
3D reconstruction from a single RGB image is a challenging problem in computer vision. Previous methods are usually solely data-driven, which lead to inaccurate 3D shape recovery and limited generalization capability. In this work, we focus on object
-level 3D reconstruction and present a geometry-based end-to-end deep learning framework that first detects the mirror plane of reflection symmetry that commonly exists in man-made objects and then predicts depth maps by finding the intra-image pixel-wise correspondence of the symmetry. Our method fully utilizes the geometric cues from symmetry during the test time by building plane-sweep cost volumes, a powerful tool that has been used in multi-view stereopsis. To our knowledge, this is the first work that uses the concept of cost volumes in the setting of single-image 3D reconstruction. We conduct extensive experiments on the ShapeNet dataset and find that our reconstruction method significantly outperforms the previous state-of-the-art single-view 3D reconstruction networks in term of the accuracy of camera poses and depth maps, without requiring objects being completely symmetric. Code is available at https://github.com/zhou13/symmetrynet.
