We discuss the possibility to measure in present experiments, especially LHCb, the non leptonic decay branching ratio $B to D pi$, and emphasize phenomenological implications on $B to D l u$ semileptonic decay. We have estimated by lattice QCD the $
D$ decay constant $f_{D}$ that parameterizes the $D$ emission contribution to the Class-III non leptonic decay $B^- to D^0 pi^-$. In addition, we provide a new estimate of the decay constants $f_{D_{s,q}}$ which read $f_{D_{s}}=252(3)$ MeV and $f_{D_{s}}/f_{D}=1.23(1)(1)$.
We report on an estimate of alpha_s, renormalised in the MSbar scheme at the tau and Z^0 mass scales, by means of lattice QCD. Our major improvement compared to previous lattice calculations is that, for the first time, no perturbative treatment at t
he charm threshold has been required since we have used statistical samples of gluon fields built by incorporating the vacuum polarisation effects of u/d, s and c sea quarks. Extracting alpha_s in the Taylor scheme from the lattice measurement of the ghost-ghost-gluon vertex, we obtain alpha_s^{MSbar}(m^2_Z)=0.1200(14) and alpha_s^{MSbar}(m^2_tau)=0.339(13).
