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Defects, and in particular topological defects, are architectural motifs that play a crucial role in natural materials. Here we provide a systematic strategy to introduce such defects in mechanical metamaterials. We first present metamaterials that a re a mechanical analogue of spin systems with tunable ferromagnetic and antiferromagnetic interactions, then design an exponential number of frustration-free metamaterials, and finally introduce topological defects by rotating a string of building blocks in these metamaterials. We uncover the distinct mechanical signature of topological defects by experiments and simulations, and leverage this to design complex metamaterials in which we can steer deformations and stresses towards parts of the system. Our work presents a new avenue to systematically include spatial complexity, frustration, and topology in mechanical metamaterials.
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