We predict the effect of the roton instability for a two-dimensional weakly interacting gas of tilted dipoles in a single homogeneous quantum layer. Being typical for strongly correlated systems, the roton phenomena appear to occur in a weakly intera
cting gas. It is important that in contrast to a system of normal to wide layer dipoles, breaking of the rotational symmetry for a system of tilted dipoles leads to the convergence of the condensate depletion even up to the threshold of the roton instability, with mean-field approach being valid. Predicted effects can be observed in a wide class of dipolar systems. We suggest observing predicted phenomena for systems of ultracold atoms and polar molecules in optical lattices, and estimate optimal experimental parameters.
