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A quite flourishing research thread in the recent literature on component-based systems is concerned with the algebraic properties of different classes of connectors. In a recent paper, an algebra of stateless connectors was presented that consists o f five kinds of basic connectors, namely symmetry, synchronization, mutual exclusion, hiding and inaction, plus their duals, and it was shown how they can be freely composed in series and in parallel to model sophisticated glues. In this paper we explore the expressiveness of stateful connectors obtained by adding one-place buffers or unbounded buffers to the stateless connectors. The main results are: i) we show how different classes of connectors exactly correspond to suitable classes of Petri nets equipped with compositional interfaces, called nets with boundaries; ii) we show that the difference between strong and weak semantics in stateful connectors is reflected in the semantics of nets with boundaries by moving from the classic step semantics (strong case) to a novel banking semantics (weak case), where a step can be executed by taking some debit tokens to be given back during the same step; iii) we show that the corresponding bisimilarities are congruences (w.r.t. composition of connectors in series and in parallel); iv) we show that suitable monoidality laws, like those arising when representing stateful connectors in the tile model, can nicely capture concurrency (in the sense of step semantics) aspects; and v) as a side result, we provide a basic algebra, with a finite set of symbols, out of which we can compose all P/T nets with boundaries, fulfilling a long standing quest.
Delays in biological systems may be used to model events for which the underlying dynamics cannot be precisely observed, or to provide abstraction of some behavior of the system resulting more compact models. In this paper we enrich the stochastic pr ocess algebra Bio-PEPA, with the possibility of assigning delays to actions, yielding a new non-Markovian process algebra: Bio-PEPAd. This is a conservative extension meaning that the original syntax of Bio-PEPA is retained and the delay specification which can now be associated with actions may be added to existing Bio-PEPA models. The semantics of the firing of the actions with delays is the delay-as-duration approach, earlier presented in papers on the stochastic simulation of biological systems with delays. These semantics of the algebra are given in the Starting-Terminating style, meaning that the state and the completion of an action are observed as two separate events, as required by delays. Furthermore we outline how to perform stochastic simulation of Bio-PEPAd systems and how to automatically translate a Bio-PEPAd system into a set of Delay Differential Equations, the deterministic framework for modeling of biological systems with delays. We end the paper with two example models of biological systems with delays to illustrate the approach.
In the last months several ballon and satellite experiments improved significantly our knowledge of cosmic rays (CR) spectra at high energy. In particular CREAM allowed to measure B/C, C/O and N/O up to 1 TeV and PAMELA the anti-p/p ratio up to 100 G eV with unprecedented accuracy. These measurements offer a valuable probe of CR propagation properties. We performed a statistical analysis to test the compatibility of these results, as well as other most significant experimental data, with the predictions of a new numerical CR diffusion package (DRAGON). We found that above 1 GeV all data are consistent with a diffusion scenario in a well defined range of values of the diffusion coefficient energy power index and normalization.
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