Understanding the chemical evolution of young (high-mass) star-forming regions is a central topic in star formation research. Chemistry is employed as a unique tool 1) to investigate the underlying physical processes and 2) to characterize the evolut
ion of the chemical composition. We observed a sample of 59 high-mass star-forming regions at different evolutionary stages varying from the early starless phase of infrared dark clouds to high-mass protostellar objects to hot molecular cores and, finally, ultra-compact HII regions at 1mm and 3mm with the IRAM 30m telescope. We determined their large-scale chemical abundances and found that the chemical composition evolves along with the evolutionary stages. On average, the molecular abundances increase with time. We modeled the chemical evolution, using a 1D physical model where density and temperature vary from stage to stage coupled with an advanced gas-grain chemical model and derived the best-fit chi^2 values of all relevant parameters. A satisfying overall agreement between observed and modeled column densities for most of the molecules was obtained. With the best-fit model we also derived a chemical age for each stage, which gives the timescales for the transformation between two consecutive stages. The best-fit chemical ages are ~10,000 years for the IRDC stage, ~60,000 years for the HMPO stage, ~40,000 years for the HMC stage, and ~10,000 years for the UCHII stage. The total chemical timescale for the entire evolutionary sequence of the high-mass star formation process is on the order of 10^5 years, which is consistent with theoretical estimates. Furthermore, based on the approach of a multiple-line survey of unresolved data, we were able to constrain an intuitive and reasonable physical and chemical model. The results of this study can be used as chemical templates for the different evolutionary stages in high-mass star formation.
