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We consider conformal N=2 super Yang-Mills theories with gauge group SU(N) and Nf=2N fundamental hypermultiplets in presence of a circular 1/2-BPS Wilson loop. It is natural to conjecture that the matrix model which describes the expectation value of this system also encodes the one-point functions of chiral scalar operators in presence of the Wilson loop. We obtain evidence of this conjecture by successfully comparing, at finite N and at the two-loop order, the one-point functions computed in field theory with the vacuum expectation values of the corresponding normal-ordered operators in the matrix model. For the part of these expressions with transcendentality zeta(3), we also obtain results in the large-N limit that are exact in the t Hooft coupling lambda.
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