An anisotropic power spectrum will have a clear signature in the 21cm radiation from high-redshift hydrogen. We calculate the expected power spectrum of the intensity fluctuations in neutral hydrogen from before the epoch of reionization, and predict
the accuracy to which future experiments could constrain a quadrupole anisotropy in the power spectrum. We find that the Square Kilometer Array will have marginal detection abilities for this signal at z~17 if the process of reionization has not yet started; reionization could enhance the detectability substantially. Pushing to higher redshifts and higher sensitivity will allow highly precise (percent level) measurements of anisotropy.
