A quaternionic version of the Calabi problem on Monge-Ampere equation is introduced. It is a quaternionic Monge-Ampere equation on a compact hypercomplex manifold with an HKT-metric. The equation is non-linear elliptic of second order. For a hypercom
plex manifold with holonomy in SL(n;H), uniqueness (up to a constant) of a solution is proven, as well as the zero order a priori estimate. The existence of solution is conjectured, similar to Calabi-Yau theorem. We reformulate this quaternionic equation as a special case of a complex Hessian equation, making sense on any complex manifold.
