We study universal enveloping Hopf algebras of Lie algebras in the category of weakly complete vector spaces over the real and complex field.
Suppose that $X=G/K$ is the quotient of a locally compact group by a closed subgroup. If $X$ is locally contractible and connected, we prove that $X$ is a manifold. If the $G$-action is faithful, then $G$ is a Lie group.