Reducing estimation bias in adaptively changing monitoring networks with preferential site selection

This paper explores the topic of preferential sampling, specifically situations where monitoring sites in environmental networks are preferentially located by the designers. This means the data arising from such networks may not accurately characterize the spatio-temporal field they intend to monitor. Approaches that have been developed to mitigate the effects of preferential sampling in various contexts are reviewed and, building on these approaches, a general framework for dealing with the effects of preferential sampling in environmental monitoring is proposed. Strategies for implementation are proposed, leading to a method for improving the accuracy of official statistics used to report trends and inform regulatory policy. An essential feature of the method is its capacity to learn the preferential selection process over time and hence to reduce bias in these statistics. Simulation studies suggest dramatic reductions in bias are possible. A case study demonstrates use of the method in assessing the levels of air pollution due to black smoke in the UK over an extended period (1970-1996). In particular, dramatic reductions in the estimates of the number of sites out of compliance are observed.

Estimating exposure response functions using ambient pollution concentrations

This paper presents an approach to estimating the health effects of an environmental hazard. The approach is general in nature, but is applied here to the case of air pollution. It uses a computer model involving ambient pollution and temperature inputs, to simulate the exposures experienced by individuals in an urban area, whilst incorporating the mechanisms that determine exposures. The output from the model comprises a set of daily exposures for a sample of individuals from the population of interest. These daily exposures are approximated by parametric distributions, so that the predictive exposure distribution of a randomly selected individual can be generated. These distributions are then incorporated into a hierarchical Bayesian framework (with inference using Markov Chain Monte Carlo simulation) in order to examine the relationship between short-term changes in exposures and health outcomes, whilst making allowance for long-term trends, seasonality, the effect of potential confounders and the possibility of ecological bias. The paper applies this approach to particulate pollution (PM$_{10}$) and respiratory mortality counts for seniors in greater London ($geq$65 years) during 1997. Within this substantive epidemiological study, the effects on health of ambient concentrations and (estimated) personal exposures are compared.