PET imaging is a non-invasive technique for particle range verification in proton therapy. It is based on measuring the beta+ annihilations caused by nuclear interactions of the protons in the patient. In this work we present measurements for proton
range verification in phantoms, performed at the CNAO particle therapy treatment center in Pavia, Italy, with our 10 x 10 cm^2 planar PET prototype DoPET. PMMA phantoms were irradiated with mono-energetic proton beams and clinical treatment plans, and PET data were acquired during and shortly after proton irradiation. We created 1-D profiles of the beta+ activity along the proton beam-axis, and evaluated the difference between the proximal rise and the distal fall-off position of the activity distribution. A good agreement with FLUKA Monte Carlo predictions was obtained. We also assessed the system response when the PMMA phantom contained an air cavity. The system was able to detect these cavities quickly after irradiation.
Organic scintillators are often chosen as radiation detectors for their fast decay time and their low Z, while inorganic ones are used when high light ields are required. In this paper we show that a para-terphenyl based detector has a blend of prope
rties of the two categories that can be optimal for energy and position measurements of low energy charged particles. On 0.1% diphenylbutadiene doped para-terphenyl samples we measure a light yield 3.5+-0.2 times larger than a typical organic scintillator (EJ-200), and a rejection power for 660 keV photons, with respect to electrons of the same energy, ranging between 3-11%, depending on the signal threshold. We also measure a light attenuation length = 4.73+-0.06 mm and we demonstrate that, with the measurements performed in this paper, a simulation based on FLUKA can properly reproduce the measured spectra.
Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be developed
and introduced into clinical use. The measurement of the fluxes of the secondary particles produced by the hadron beam is of fundamental importance in the design of any dose monitoring device and is eagerly needed to tune Monte Carlo simulations. We report the measurements done with charged secondary particles produced from the interaction of a 80 MeV/u fully stripped carbon ion beam at the INFN Laboratori Nazionali del Sud, Catania, with a Poly-methyl methacrylate target. Charged secondary particles, produced at 90$degree$ with respect to the beam axis, have been tracked with a drift chamber, while their energy and time of flight has been measured by means of a LYSO scintillator. Secondary protons have been identified exploiting the energy and time of flight information, and their emission region has been reconstructed backtracking from the drift chamber to the target. Moreover a position scan of the target indicates that the reconstructed emission region follows the movement of the expected Bragg peak position. Exploting the reconstruction of the emission region, an accuracy on the Bragg peak determination in the submillimeter range has been obtained. The measured differential production rate for protons produced with $E^{rm Prod}_{rm kin} >$ 83 MeV and emitted at 90$degree$ with respect to the beam line is: $dN_{rm P}/(dN_{rm C}dOmega)(E^{rm Prod}_{rm kin} > 83 {rm ~MeV}, theta=90degree)= (2.69pm 0.08_{rm stat} pm 0.12_{rm sys})times 10^{-4} sr^{-1}$.
Primary GCR interact with the Earths atmosphere originating atmospheric showers, thus giving rise to fluxes of secondary particles in the atmosphere. Electromagnetic and hadronic interactions interplay in the production of these particles, whose dete
ction is performed by means of complementary techniques in different energy ranges and at different depths in the atmosphere, down to the Earths surface. Monte Carlo codes are essential calculation tools which can describe the complexity of the physics of these phenomena, thus allowing the analysis of experimental data. However, these codes are affected by important uncertainties, concerning, in particular, hadronic physics at high energy. In this paper we shall report some results concerning inclusive particle fluxes and atmospheric shower properties as obtained using the FLUKA transport and interaction code. Some emphasis will also be given to the validation of the physics models of FLUKA involved in these calculations.
The paper is considering an opportunity for the CERN/GranSasso (CNGS) neutrino complex, concurrent time-wise with T2K and NOvA, to search for theta_13 oscillations and CP violation. Compared with large water Cherenkov (T2K) and fine grained scintilla
tors (NOvA), the LAr-TPC offers a higher detection efficiency and a lower backgrounds, since virtually all channels may be unambiguously recognized. The present proposal, called MODULAr, describes a 20 kt fiducial volume LAr-TPC, following very closely the technology developed for the ICARUS-T60o, and is focused on the following activities, for which we seek an extended international collaboration: (1) the neutrino beam from the CERN 400 GeV proton beam and an optimised horn focussing, eventually with an increased intensity in the framework of the LHC accelerator improvement program; (2) A new experimental area LNGS-B, of at least 50000 m3 at 10 km off-axis from the main Laboratory, eventually upgradable to larger sizes. A location is under consideration at about 1.2 km equivalent water depth; (3) A new LAr Imaging detector of at least 20 kt fiducial mass. Such an increase in the volume over the current ICARUS T600 needs to be carefully considered. It is concluded that a very large mass is best realised with a set of many identical, independent units, each of 5 kt, cloning the technology of the T600. Further phases may foresee extensions of MODULAr to meet future physics goals. The experiment might reasonably be operational in about 4/5 years, provided a new hall is excavated in the vicinity of the Gran Sasso Laboratory and adequate funding and participation are made available.
