We consider a second-order parabolic equation in $bR^{d+1}$ with possibly unbounded lower order coefficients. All coefficients are assumed to be only measurable in the time variable and locally Holder continuous in the space variables. We show that g
lobal Schauder estimates hold even in this case. The proof introduces a new localization procedure. Our results show that the constant appearing in the classical Schauder estimates is in fact independent of the $L_{infty}$-norms of the lower order coefficients. We also give a proof of uniqueness which is of independent interest even in the case of bounded coefficients.