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We show that a viscoelastic thin sheet driven out of equilibrium by active structural remodelling develops a rich variety of shapes as a result of a competition between viscous relaxation and activity. In the regime where active processes are faster than viscoelastic relaxation, wrinkles that are formed due to remodelling are unable to relax to a configuration that minimises the elastic energy and the sheet is inherently out of equilibrium. We argue that this non-equilibrium regime is of particular interest in biology as it allows the system to access morphologies that are unavailable if restricted to the adiabatic evolution between configurations that minimise the elastic energy alone. Here, we introduce activity using the formalism of evolving target metric and showcase the diversity of wrinkling morphologies arising from out of equilibrium dynamics.
Mechanical signaling plays a key role in biological processes like embryo development and cancer growth. One prominent way to probe mechanical properties of tissues is to study their response to externally applied forces. Using a particle-based model featuring random apoptosis and environment-dependent division rates, we evidence a crossover from linear flow to a shear-thinning regime with increasing shear rate. To rationalize this non-linear flow we derive a theoretical mean-field scenario that accounts for the interplay of mechanical and active noise in local stresses. These noises are respectively generated by the elastic response of the cell matrix to cell rearrangements and by the internal activity.
The statistical thermodynamics of straight rigid rods of length $k$ on triangular lattices was developed on a generalization in the spirit of the lattice-gas model and the classical Guggenheim-DiMarzio approximation. In this scheme, the Helmholtz fre e energy and its derivatives were written in terms of the order parameter $delta$, which characterizes the nematic phase occurring in the system at intermediate densities. Then, using the principle of minimum free energy with $delta$ as a parameter, the main adsorption properties were calculated. Comparisons with Monte Carlo simulations and experimental data were performed in order to evaluate the reaches and limitations of the theoretical model.
Numerical simulations and finite-size scaling analysis have been carried out to study the percolation behavior of straight rigid rods of length $k$ ($k$-mers) on two-dimensional square lattices. The $k$-mers, containing $k$ identical units (each one occupying a lattice site), were adsorbed at equilibrium on the lattice. The process was monitored by following the probability $R_{L,k}(theta)$ that a lattice composed of $L times L$ sites percolates at a concentration $theta$ of sites occupied by particles of size $k$. A nonmonotonic size dependence was observed for the percolation threshold, which decreases for small particles sizes, goes through a minimum, and finally asymptotically converges towards a definite value for large segments. This striking behavior has been interpreted as a consequence of the isotropic-nematic phase transition occurring in the system for large values of $k$. Finally, the universality class of the model was found to be the same as for the random percolation model.
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