Recent papers have suggested that transfer learning can outperform sophisticated meta-learning methods for few-shot image classification. We take this hypothesis to its logical conclusion, and suggest the use of an ensemble of high-quality, pre-train
ed feature extractors for few-shot image classification. We show experimentally that a library of pre-trained feature extractors combined with a simple feed-forward network learned with an L2-regularizer can be an excellent option for solving cross-domain few-shot image classification. Our experimental results suggest that this simpler sample-efficient approach far outperforms several well-established meta-learning algorithms on a variety of few-shot tasks.
We present a new approach, called meta-meta classification, to learning in small-data settings. In this approach, one uses a large set of learning problems to design an ensemble of learners, where each learner has high bias and low variance and is sk
illed at solving a specific type of learning problem. The meta-meta classifier learns how to examine a given learning problem and combine the various learners to solve the problem. The meta-meta learning approach is especially suited to solving few-shot learning tasks, as it is easier to learn to classify a new learning problem with little data than it is to apply a learning algorithm to a small data set. We evaluate the approach on a one-shot, one-class-versus-all classification task and show that it is able to outperform traditional meta-learning as well as ensembling approaches.
The present work provides a new approach to evolve ligand structures which represent possible drug to be docked to the active site of the target protein. The structure is represented as a tree where each non-empty node represents a functional group.
It is assumed that the active site configuration of the target protein is known with position of the essential residues. In this paper the interaction energy of the ligands with the protein target is minimized. Moreover, the size of the tree is difficult to obtain and it will be different for different active sites. To overcome the difficulty, a variable tree size configuration is used for designing ligands. The optimization is done using a novel Neighbourhood Based Genetic Algorithm (NBGA) which uses dynamic neighbourhood topology. To get variable tree size, a variable-length version of the above algorithm is devised. To judge the merit of the algorithm, it is initially applied on the well known Travelling Salesman Problem (TSP).
