This paper deals essentially with affine or projective transformations of Lie groups endowed with a flat left invariant affine or projective structure. These groups are called flat affine or flat projective Lie groups. Our main results determine Lie
groups admitting flat bi-invariant affine or projective structures. These groups could play an essential role in the study of homogeneous spaces $M=G/H$ admitting flat affine or flat projective structures invariant under the natural action of $G$ on $M$. A. Medina asked several years ago if the group of affine transformations of a flat affine Lie group is a flat projective Lie group. In this work we provide a partial possitive answer to this question.
