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When controllers (brains) and morphologies (bodies) of robots simultaneously evolve, this can lead to a problem, namely the brain & body mismatch problem. In this research, we propose a solution of lifetime learning. We set up a system where modular robots can create offspring that inherit the bodies of parents by recombination and mutation. With regards to the brains of the offspring, we use two methods to create them. The first one entails solely evolution which means the brain of a robot child is inherited from its parents. The second approach is evolution plus learning which means the brain of a child is inherited as well, but additionally is developed by a learning algorithm - RevDEknn. We compare these two methods by running experiments in a simulator called Revolve and use efficiency, efficacy, and the morphology intelligence of the robots for the comparison. The experiments show that the evolution plus learning method does not only lead to a higher fitness level, but also to more morphologically evolving robots. This constitutes a quantitative demonstration that changes in the brain can induce changes in the body, leading to the concept of morphological intelligence, which is quantified by the learning delta, meaning the ability of a morphology to facilitate learning.
Models in systems biology are mathematical descriptions of biological processes that are used to answer questions and gain a better understanding of biological phenomena. Dynamic models represent the network through rates of the production and consum ption for the individual species. The ordinary differential equations that describe rates of the reactions in the model include a set of parameters. The parameters are important quantities to understand and analyze biological systems. Moreover, the perturbation of the kinetic parameters are correlated with upregulation of the system by cell-intrinsic and cell-extrinsic factors, including mutations and the environment changes. Here, we aim at using well-established models of biological pathways to identify parameter values and point their potential perturbation/deviation. We present our population-based optimization framework that is able to identify kinetic parameters in the dynamic model based on only input and output data (i.e., timecourses of selected metabolites). Our approach can deal with the identification of the non-measurable parameters as well as with discovering deviation of the parameters. We present our proposed optimization framework on the example of the well-studied glycolytic pathway in Saccharomyces cerevisiae.
Differential evolution (DE) is a well-known type of evolutionary algorithms (EA). Similarly to other EA variants it can suffer from small populations and loose diversity too quickly. This paper presents a new approach to mitigate this issue: We propo se to generate new candidate solutions by utilizing reversible linear transformation applied to a triplet of solutions from the population. In other words, the population is enlarged by using newly generated individuals without evaluating their fitness. We assess our methods on three problems: (i) benchmark function optimization, (ii) discovering parameter values of the gene repressilator system, (iii) learning neural networks. The empirical results indicate that the proposed approach outperforms vanilla DE and a version of DE with applying differential mutation three times on all testbeds.
Natural lifeforms specialise to their environmental niches across many levels; from low-level features such as DNA and proteins, through to higher-level artefacts including eyes, limbs, and overarching body plans. We propose Multi-Level Evolution (ML E), a bottom-up automatic process that designs robots across multiple levels and niches them to tasks and environmental conditions. MLE concurrently explores constituent molecular and material building blocks, as well as their possible assemblies into specialised morphological and sensorimotor configurations. MLE provides a route to fully harness a recent explosion in available candidate materials and ongoing advances in rapid manufacturing processes. We outline a feasible MLE architecture that realises this vision, highlight the main roadblocks and how they may be overcome, and show robotic applications to which MLE is particularly suited. By forming a research agenda to stimulate discussion between researchers in related fields, we hope to inspire the pursuit of multi-level robotic design all the way from material to machine.
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