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We present the results of a search for molecular gas emission from a star-forming galaxy at z = 4.9. The galaxy benefits from magnification of 22 +/- 5x due to strong gravitational lensing by the foreground cluster MS1358+62. We target the CO(5-4) em ission at a known position and redshift from existing Hubble Space Telescope/ACS imaging and Gemini/NIFS [OII]3727 imaging spectroscopy, and obtain a tentative detection at the 4.3sigma level with a flux of 0.104 +/- 0.024Jkm/s. From the CO line luminosity and assuming a CO-to-H2 conversion factor alpha=2, we derive a gas mass M_gas ~ 1^{+1}_{-0.6} x 10^9 M_sun. Combined with the existing data, we derive a gas fraction Mgas/(Mgas + M*) = 0.59^{+0.11}_{-0.06}. The faint line flux of this galaxy highlights the difficulty of observing molecular gas in representative galaxies at this epoch, and suggests that routine detections of similar galaxies in the absence of gravitational lensing will remain challenging even with ALMA in full science operations.
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