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Least-squares fitting of Gaussian spots on graphics processing units

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 Added by Marcel Leutenegger
 Publication date 2021
and research's language is English




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The investigation of samples with a spatial resolution in the nanometer range relies on the precise and stable positioning of the sample. Due to inherent mechanical instabilities of typical sample stages in optical microscopes, it is usually required to control and/or monitor the sample position during the acquisition. The tracking of sparsely distributed fiducial markers at high speed allows stabilizing the sample position at millisecond time scales. For this purpose, we present a scalable fitting algorithm with significantly improved performance for two-dimensional Gaussian fits as compared to Gpufit.

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We present a novel implementation of the modal discontinuous Galerkin (DG) method for hyperbolic conservation laws in two dimensions on graphics processing units (GPUs) using NVIDIAs Compute Unified Device Architecture (CUDA). Both flexible and highly accurate, DG methods accommodate parallel architectures well as their discontinuous nature produces element-local approximations. High performance scientific computing suits GPUs well, as these powerful, massively parallel, cost-effective devices have recently included support for double-precision floating point numbers. Computed examples for Euler equations over unstructured triangle meshes demonstrate the effectiveness of our implementation on an NVIDIA GTX 580 device. Profiling of our method reveals performance comparable to an existing nodal DG-GPU implementation for linear problems.
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A computational fluid dynamics (CFD) simulation framework for predicting complex flows is developed on the Tensor Processing Unit (TPU) platform. The TPU architecture is featured with accelerated performance of dense matrix multiplication, large high bandwidth memory, and a fast inter-chip interconnect, which makes it attractive for high-performance scientific computing. The CFD framework solves the variable-density Navier-Stokes equation using a Low-Mach approximation, and the governing equations are discretized by a finite difference method on a collocated structured mesh. It uses the graph-based TensorFlow as the programming paradigm. The accuracy and performance of this framework is studied both numerically and analytically, specifically focusing on effects of TPU-native single precision floating point arithmetic on solution accuracy. The algorithm and implementation are validated with canonical 2D and 3D Taylor Green vortex simulations. To demonstrate the capability for simulating turbulent flows, simulations are conducted for two configurations, namely the decaying homogeneous isotropic turbulence and a turbulent planar jet. Both simulations show good statistical agreement with reference solutions. The performance analysis shows a linear weak scaling and a super-linear strong scaling up to a full TPU v3 pod with 2048 cores.
We conduct a study and comparison of superiorization and optimization approaches for the reconstruction problem of superiorized/regularized least-squares solutions of underdetermined linear equations with nonnegativity variable bounds. Regarding superiorization, the state of the art is examined for this problem class, and a novel approach is proposed that employs proximal mappings and is structurally similar to the established forward-backward optimization approach. Regarding convex optimization, accelerated forward-backward splitting with inexact proximal maps is worked out and applied to both the natural splitting least-squares term/regularizer and to the reverse splitting regularizer/least-squares term. Our numerical findings suggest that superiorization can approach the solution of the optimization problem and leads to comparable results at significantly lower costs, after appropriate parameter tuning. On the other hand, applying accelerated forward-backward optimization to the reverse splitting slightly outperforms superiorization, which suggests that convex optimization can approach superiorization too, using a suitable problem splitting.
The null distributed controllability of the semilinear heat equation $y_t-Delta y + g(y)=f ,1_{omega}$, assuming that $g$ satisfies the growth condition $g(s)/(vert svert log^{3/2}(1+vert svert))rightarrow 0$ as $vert svert rightarrow infty$ and that $g^primein L^infty_{loc}(mathbb{R})$ has been obtained by Fernandez-Cara and Zuazua in 2000. The proof based on a fixed point argument makes use of precise estimates of the observability constant for a linearized heat equation. It does not provide however an explicit construction of a null control. Assuming that $g^primein W^{s,infty}(mathbb{R})$ for one $sin (0,1]$, we construct an explicit sequence converging strongly to a null control for the solution of the semilinear equation. The method, based on a least-squares approach, generalizes Newton type methods and guarantees the convergence whatever be the initial element of the sequence. In particular, after a finite number of iterations, the convergence is super linear with a rate equal to $1+s$. Numerical experiments in the one dimensional setting support our analysis.
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