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Register a new userSuper-Resolution of Brain MRI Images using Overcomplete Dictionaries and Nonlocal Similarity
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Added by
Bin Song
Publication date
2019
fields
Informatics Engineering
and research's language is
English
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Recently, the Magnetic Resonance Imaging (MRI) images have limited and unsatisfactory resolutions due to various constraints such as physical, technological and economic considerations. Super-resolution techniques can obtain high-resolution MRI images. The traditional methods obtained the resolution enhancement of brain MRI by interpolations, affecting the accuracy of the following diagnose process. The requirement for brain image quality is fast increasing. In this paper, we propose an image super-resolution (SR) method based on overcomplete dictionaries and inherent similarity of an image to recover the high-resolution (HR) image from a single low-resolution (LR) image. We explore the nonlocal similarity of the image to tentatively search for similar blocks in the whole image and present a joint reconstruction method based on compressive sensing (CS) and similarity constraints. The sparsity and self-similarity of the image blocks are taken as the constraints. The proposed method is summarized in the following steps. First, a dictionary classification method based on the measurement domain is presented. The image blocks are classified into smooth, texture and edge parts by analyzing their features in the measurement domain. Then, the corresponding dictionaries are trained using the classified image blocks. Equally important, in the reconstruction part, we use the CS reconstruction method to recover the HR brain MRI image, considering both nonlocal similarity and the sparsity of an image as the constraints. This method performs better both visually and quantitatively than some existing methods.
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A central problem in neuroscience is reconstructing neuronal circuits on the synapse level. Due to a wide range of scales in brain architecture such reconstruction requires imaging that is both high-resolution and high-throughput. Existing electron microscopy (EM) techniques possess required resolution in the lateral plane and either high-throughput or high depth resolution but not both. Here, we exploit recent advances in unsupervised learning and signal processing to obtain high depth-resolution EM images computationally without sacrificing throughput. First, we show that the brain tissue can be represented as a sparse linear combination of localized basis functions that are learned using high-resolution datasets. We then develop compressive sensing-inspired techniques that can reconstruct the brain tissue from very few (typically 5) tomographic views of each section. This enables tracing of neuronal processes and, hence, high throughput reconstruction of neural circuits on the level of individual synapses.
Magnetic resonance image (MRI) in high spatial resolution provides detailed anatomical information and is often necessary for accurate quantitative analysis. However, high spatial resolution typically comes at the expense of longer scan time, less spatial coverage, and lower signal to noise ratio (SNR). Single Image Super-Resolution (SISR), a technique aimed to restore high-resolution (HR) details from one single low-resolution (LR) input image, has been improved dramatically by recent breakthroughs in deep learning. In this paper, we introduce a new neural network architecture, 3D Densely Connected Super-Resolution Networks (DCSRN) to restore HR features of structural brain MR images. Through experiments on a dataset with 1,113 subjects, we demonstrate that our network outperforms bicubic interpolation as well as other deep learning methods in restoring 4x resolution-reduced images.
We propose a two-stage algorithm for the super-resolution of MR images from their low-frequency k-space samples. In the first stage we estimate a resolution-independent mask whose zeros represent the edges of the image. This builds off recent work extending the theory of sampling signals of finite rate of innovation (FRI) to two-dimensional curves. We enable its application to MRI by proposing extensions of the signal models allowed by FRI theory, and by developing a more robust and efficient means to determine the edge mask. In the second stage of the scheme, we recover the super-resolved MR image using the discretized edge mask as an image prior. We evaluate our scheme on simulated single-coil MR data obtained from analytical phantoms, and compare against total variation reconstructions. Our experiments show improved performance in both noiseless and noisy settings.
Partial voluming (PV) is arguably the last crucial unsolved problem in Bayesian segmentation of brain MRI with probabilistic atlases. PV occurs when voxels contain multiple tissue classes, giving rise to image intensities that may not be representative of any one of the underlying classes. PV is particularly problematic for segmentation when there is a large resolution gap between the atlas and the test scan, e.g., when segmenting clinical scans with thick slices, or when using a high-resolution atlas. In this work, we present PV-SynthSeg, a convolutional neural network (CNN) that tackles this problem by directly learning a mapping between (possibly multi-modal) low resolution (LR) scans and underlying high resolution (HR) segmentations. PV-SynthSeg simulates LR images from HR label maps with a generative model of PV, and can be trained to segment scans of any desired target contrast and resolution, even for previously unseen modalities where neither images nor segmentations are available at training. PV-SynthSeg does not require any preprocessing, and runs in seconds. We demonstrate the accuracy and flexibility of the method with extensive experiments on three datasets and 2,680 scans. The code is available at https://github.com/BBillot/SynthSeg.
In recent years, much research has been conducted on image super-resolution (SR). To the best of our knowledge, however, few SR methods were concerned with compressed images. The SR of compressed images is a challenging task due to the complicated compression artifacts, while many images suffer from them in practice. The intuitive solution for this difficult task is to decouple it into two sequential but independent subproblems, i.e., compression artifacts reduction (CAR) and SR. Nevertheless, some useful details may be removed in CAR stage, which is contrary to the goal of SR and makes the SR stage more challenging. In this paper, an end-to-end trainable deep convolutional neural network is designed to perform SR on compressed images (CISRDCNN), which reduces compression artifacts and improves image resolution jointly. Experiments on compressed images produced by JPEG (we take the JPEG as an example in this paper) demonstrate that the proposed CISRDCNN yields state-of-the-art SR performance on commonly used test images and imagesets. The results of CISRDCNN on real low quality web images are also very impressive, with obvious quality enhancement. Further, we explore the application of the proposed SR method in low bit-rate image coding, leading to better rate-distortion performance than JPEG.
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