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Non-Learning based Deep Parallel MRI Reconstruction (NLDpMRI)

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 Publication date 2018
and research's language is English




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Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. Recently, the deep learning-based MRI reconstruction techniques were suggested to accelerate MR image acquisition. The most common issues in any deep learning-based MRI reconstruction approaches are generalizability and transferability. For different MRI scanner configurations using these approaches, the network must be trained from scratch every time with new training dataset, acquired under new configurations, to be able to provide good reconstruction performance. Here, we propose a new generalized parallel imaging method based on deep neural networks called NLDpMRI to reduce any structured aliasing ambiguities related to the different k-space undersampling patterns for accelerated data acquisition. Two loss functions including non-regularized and regularized are proposed for parallel MRI reconstruction using deep network optimization and we reconstruct MR images by optimizing the proposed loss functions over the network parameters. Unlike any deep learning-based MRI reconstruction approaches, our method doesnt include any training step that the network learns from a large number of training samples and it only needs the single undersampled multi-coil k-space data for reconstruction. Also, the proposed method can handle k-space data with different undersampling patterns, and the different number of coils. Experimental results show that the proposed method outperforms the current state-of-the-art GRAPPA method and the deep learning-based variational network method.

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We propose a novel deep neural network architecture by mapping the robust proximal gradient scheme for fast image reconstruction in parallel MRI (pMRI) with regularization function trained from data. The proposed network learns to adaptively combine the multi-coil images from incomplete pMRI data into a single image with homogeneous contrast, which is then passed to a nonlinear encoder to efficiently extract sparse features of the image. Unlike most of existing deep image reconstruction networks, our network does not require knowledge of sensitivity maps, which can be difficult to estimate accurately, and have been a major bottleneck of image reconstruction in real-world pMRI applications. The experimental results demonstrate the promising performance of our method on a variety of pMRI imaging data sets.
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. Conventional MRI reconstruction methods for fast MRI acquisition mostly relied on different regularizers which represent analytical models of sparsity. However, recent data-driven methods based on deep learning has resulted in promising improvements in image reconstruction algorithms. In this paper, we propose a deep plug-and-play prior framework for parallel MRI reconstruction problems which utilize a deep neural network (DNN) as an advanced denoiser within an iterative method. This, in turn, enables rapid acquisition of MR images with improved image quality. The proposed method was compared with the reconstructions using the clinical gold standard GRAPPA method. Our results with undersampled data demonstrate that our method can deliver considerably higher quality images at high acceleration factors in comparison to clinical gold standard method for MRI reconstructions. Our proposed reconstruction enables an increase in acceleration factor, and a reduction in acquisition time while maintaining high image quality.
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. The data-driven methods based on deep neural networks have resulted in promising improvements, compared to the conventional methods, in image reconstruction algorithms. The connection between deep neural network and Ordinary Differential Equation (ODE) has been observed and studied recently. The studies show that different residual networks can be interpreted as Euler discretization of an ODE. In this paper, we propose an ODE-based deep network for MRI reconstruction to enable the rapid acquisition of MR images with improved image quality. Our results with undersampled data demonstrate that our method can deliver higher quality images in comparison to the reconstruction methods based on the standard UNet network and Residual network.
Purpose: Although recent deep energy-based generative models (EBMs) have shown encouraging results in many image generation tasks, how to take advantage of the self-adversarial cogitation in deep EBMs to boost the performance of Magnetic Resonance Imaging (MRI) reconstruction is still desired. Methods: With the successful application of deep learning in a wide range of MRI reconstruction, a line of emerging research involves formulating an optimization-based reconstruction method in the space of a generative model. Leveraging this, a novel regularization strategy is introduced in this article which takes advantage of self-adversarial cogitation of the deep energy-based model. More precisely, we advocate for alternative learning a more powerful energy-based model with maximum likelihood estimation to obtain the deep energy-based information, represented as image prior. Simultaneously, implicit inference with Langevin dynamics is a unique property of re-construction. In contrast to other generative models for reconstruction, the proposed method utilizes deep energy-based information as the image prior in reconstruction to improve the quality of image. Results: Experiment results that imply the proposed technique can obtain remarkable performance in terms of high reconstruction accuracy that is competitive with state-of-the-art methods, and does not suffer from mode collapse. Conclusion: Algorithmically, an iterative approach was presented to strengthen EBM training with the gradient of energy network. The robustness and the reproducibility of the algorithm were also experimentally validated. More importantly, the proposed reconstruction framework can be generalized for most MRI reconstruction scenarios.
Deep learning methods are the de-facto solutions to a multitude of medical image analysis tasks. Cardiac MRI segmentation is one such application which, like many others, requires a large number of annotated data so a trained network can generalize well. Unfortunately, the process of having a large number of manually curated images by medical experts is both slow and utterly expensive. In this paper, we set out to explore whether expert knowledge is a strict requirement for the creation of annotated datasets that machine learning can successfully train on. To do so, we gauged the performance of three segmentation models, namely U-Net, Attention U-Net, and ENet, trained with different loss functions on expert and non-expert groundtruth for cardiac cine-MRI segmentation. Evaluation was done with classic segmentation metrics (Dice index and Hausdorff distance) as well as clinical measurements, such as the ventricular ejection fractions and the myocardial mass. Results reveal that generalization performances of a segmentation neural network trained on non-expert groundtruth data is, to all practical purposes, as good as on expert groundtruth data, in particular when the non-expert gets a decent level of training, highlighting an opportunity for the efficient and cheap creation of annotations for cardiac datasets.
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