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Register a new userClinical Assistant Diagnosis for Electronic Medical Record Based on Convolutional Neural Network
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Zhongliang Yang
Publication date
2018
fields
Informatics Engineering
and research's language is
English
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Automatically extracting useful information from electronic medical records along with conducting disease diagnoses is a promising task for both clinical decision support(CDS) and neural language processing(NLP). Most of the existing systems are based on artificially constructed knowledge bases, and then auxiliary diagnosis is done by rule matching. In this study, we present a clinical intelligent decision approach based on Convolutional Neural Networks(CNN), which can automatically extract high-level semantic information of electronic medical records and then perform automatic diagnosis without artificial construction of rules or knowledge bases. We use collected 18,590 copies of the real-world clinical electronic medical records to train and test the proposed model. Experimental results show that the proposed model can achieve 98.67% accuracy and 96.02% recall, which strongly supports that using convolutional neural network to automatically learn high-level semantic features of electronic medical records and then conduct assist diagnosis is feasible and effective.
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$textbf{Objective}$ Develop an automatic diagnostic system which only uses textual admission information from Electronic Health Records (EHRs) and assist clinicians with a timely and statistically proved decision tool. The hope is that the tool can be used to reduce mis-diagnosis. $textbf{Materials and Methods}$ We use the real-world clinical notes from MIMIC-III, a freely available dataset consisting of clinical data of more than forty thousand patients who stayed in intensive care units of the Beth Israel Deaconess Medical Center between 2001 and 2012. We proposed a Convolutional Neural Network model to learn semantic features from unstructured textual input and automatically predict primary discharge diagnosis. $textbf{Results}$ The proposed model achieved an overall 96.11% accuracy and 80.48% weighted F1 score values on 10 most frequent disease classes, significantly outperforming four strong baseline models by at least 12.7% in weighted F1 score. $textbf{Discussion}$ Experimental results imply that the CNN model is suitable for supporting diagnosis decision making in the presence of complex, noisy and unstructured clinical data while at the same time using fewer layers and parameters that other traditional Deep Network models. $textbf{Conclusion}$ Our model demonstrated capability of representing complex medical meaningful features from unstructured clinical notes and prediction power for commonly misdiagnosed frequent diseases. It can use easily adopted in clinical setting to provide timely and statistically proved decision support. $textbf{Keywords}$ Convolutional neural network, text classification, discharge diagnosis prediction, admission information from EHRs.
Medical code assignment, which predicts medical codes from clinical texts, is a fundamental task of intelligent medical information systems. The emergence of deep models in natural language processing has boosted the development of automatic assignment methods. However, recent advanced neural architectures with flat convolutions or multi-channel feature concatenation ignore the sequential causal constraint within a text sequence and may not learn meaningful clinical text representations, especially for lengthy clinical notes with long-term sequential dependency. This paper proposes a Dilated Convolutional Attention Network (DCAN), integrating dilated convolutions, residual connections, and label attention, for medical code assignment. It adopts dilated convolutions to capture complex medical patterns with a receptive field which increases exponentially with dilation size. Experiments on a real-world clinical dataset empirically show that our model improves the state of the art.
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In this paper, we present a new automatic diagnosis method of facial acne vulgaris based on convolutional neural network. This method is proposed to overcome the shortcoming of classification types in previous methods. The core of our method is to extract features of images based on convolutional neural network and achieve classification by classifier. We design a binary classifier of skin-and-non-skin to detect skin area and a seven-classifier to achieve the classification of facial acne vulgaris and healthy skin. In the experiment, we compared the effectiveness of our convolutional neural network and the pre-trained VGG16 neural network on the ImageNet dataset. And we use the ROC curve and normal confusion matrix to evaluate the performance of the binary classifier and the seven-classifier. The results of our experiment show that the pre-trained VGG16 neural network is more effective in extracting image features. The classifiers based on the pre-trained VGG16 neural network achieve the skin detection and acne classification and have good robustness.
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