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Iterative reconstruction of SiPM light response functions in a square-shaped compact gamma camera

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 Added by Andrey Morozov
 Publication date 2016
  fields Physics
and research's language is English




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Compact gamma cameras with a square-shaped monolithic scintillator crystal and an array of silicon photomultipliers (SiPMs) are actively being developed for applications in areas such as small animal imaging, cancer diagnostics and radiotracer guided surgery. Statistical methods of position reconstruction, which are potentially superior to the traditional centroid method, require accurate knowledge of the spatial response of each photomultiplier. Using both Monte Carlo simulations and experimental data obtained with a camera prototype, we show that the spatial response of all photomultipliers (light response functions) can be parameterized with axially symmetric functions obtained iteratively from flood field irradiation data. The study was performed with a camera prototype equipped with a 30 x 30 x 2 mm3 LYSO crystal and an 8 x 8 array of SiPMs for 140 keV gamma rays. The simulations demonstrate that the images, reconstructed with the maximum likelihood method using the response obtained with the iterative approach, exhibit only minor distortions: the average difference between the reconstructed and the true positions in X and Y directions does not exceed 0.2 mm in the central area of 22 x 22 mm2 and 0.4 mm at the periphery of the camera. A similar level of image distortions is shown experimentally with the camera prototype.



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160 - A. Morozov , V. Solovov , F. Alves 2015
Statistical event reconstruction techniques can give better results for gamma cameras than the traditional centroid method. However, implementation of such techniques requires detailed knowledge of the PMT light response functions. Here we describe an iterative technique which allows to obtain the response functions from flood irradiation data without imposing strict requirements on the spatial uniformity of the event distribution. A successful application of the technique for medical gamma cameras is demonstrated using both simulated and experimental data. We show that this technique can be used for monitoring of the photomultiplier gain variations. An implementation of the iterative reconstruction technique capable of operating in real-time is also presented.
68 - P. Lv , S.L. Xiong , X.L. Sun 2018
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252 - G. Sottile , F. Russo , G. Agnetta 2013
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86 - D. Guberman 2017
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