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Register a new userA New Non-Negative Matrix Co-Factorisation Approach for Noisy Neonatal Chest Sound Separation
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Obtaining high-quality heart and lung sounds enables clinicians to accurately assess a newborns cardio-respiratory health and provide timely care. However, noisy chest sound recordings are common, hindering timely and accurate assessment. A new Non-negative Matrix Co-Factorisation-based approach is proposed to separate noisy chest sound recordings into heart, lung, and noise components to address this problem. This method is achieved through training with 20 high-quality heart and lung sounds, in parallel with separating the sounds of the noisy recording. The method was tested on 68 10-second noisy recordings containing both heart and lung sounds and compared to the current state of the art Non-negative Matrix Factorisation methods. Results show significant improvements in heart and lung sound quality scores respectively, and improved accuracy of 3.6bpm and 1.2bpm in heart and breathing rate estimation respectively, when compared to existing methods.
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Ambient sound scenes typically comprise multiple short events occurring on top of a somewhat stationary background. We consider the task of separating these events from the background, which we call foreground-background ambient sound scene separation. We propose a deep learning-based separation framework with a suitable feature normaliza-tion scheme and an optional auxiliary network capturing the background statistics, and we investigate its ability to handle the great variety of sound classes encountered in ambient sound scenes, which have often not been seen in training. To do so, we create single-channel foreground-background mixtures using isolated sounds from the DESED and Audioset datasets, and we conduct extensive experiments with mixtures of seen or unseen sound classes at various signal-to-noise ratios. Our experimental findings demonstrate the generalization ability of the proposed approach.
We present a fast variational Bayesian algorithm for performing non-negative matrix factorisation and tri-factorisation. We show that our approach achieves faster convergence per iteration and timestep (wall-clock) than Gibbs sampling and non-probabilistic approaches, and do not require additional samples to estimate the posterior. We show that in particular for matrix tri-factorisation convergence is difficult, but our variational Bayesian approach offers a fast solution, allowing the tri-factorisation approach to be used more effectively.
Non-negative Matrix Factorisation (NMF) has been extensively used in machine learning and data analytics applications. Most existing variations of NMF only consider how each row/column vector of factorised matrices should be shaped, and ignore the relationship among pairwise rows or columns. In many cases, such pairwise relationship enables better factorisation, for example, image clustering and recommender systems. In this paper, we propose an algorithm named, Relative Pairwise Relationship constrained Non-negative Matrix Factorisation (RPR-NMF), which places constraints over relative pairwise distances amongst features by imposing penalties in a triplet form. Two distance measures, squared Euclidean distance and Symmetric divergence, are used, and exponential and hinge loss penalties are adopted for the two measures respectively. It is well known that the so-called multiplicative update rules result in a much faster convergence than gradient descend for matrix factorisation. However, applying such update rules to RPR-NMF and also proving its convergence is not straightforward. Thus, we use reasonable approximations to relax the complexity brought by the penalties, which are practically verified. Experiments on both synthetic datasets and real datasets demonstrate that our algorithms have advantages on gaining close approximation, satisfying a high proportion of expected constraints, and achieving superior performance compared with other algorithms.
Multimorbidity, or the presence of several medical conditions in the same individual, has been increasing in the population, both in absolute and relative terms. However, multimorbidity remains poorly understood, and the evidence from existing research to describe its burden, determinants and consequences has been limited. Previous studies attempting to understand multimorbidity patterns are often cross-sectional and do not explicitly account for multimorbidity patterns evolution over time; some of them are based on small datasets and/or use arbitrary and narrow age ranges; and those that employed advanced models, usually lack appropriate benchmarking and validations. In this study, we (1) introduce a novel approach for using Non-negative Matrix Factorisation (NMF) for temporal phenotyping (i.e., simultaneously mining disease clusters and their trajectories); (2) provide quantitative metrics for the evaluation of disease clusters from such studies; and (3) demonstrate how the temporal characteristics of the disease clusters that result from our model can help mine multimorbidity networks and generate new hypotheses for the emergence of various multimorbidity patterns over time. We trained and evaluated our models on one of the worlds largest electronic health records (EHR), with 7 million patients, from which over 2 million where relevant to this study.
Single-microphone, speaker-independent speech separation is normally performed through two steps: (i) separating the specific speech sources, and (ii) determining the best output-label assignment to find the separation error. The second step is the main obstacle in training neural networks for speech separation. Recently proposed Permutation Invariant Training (PIT) addresses this problem by determining the output-label assignment which minimizes the separation error. In this study, we show that a major drawback of this technique is the overconfident choice of the output-label assignment, especially in the initial steps of training when the network generates unreliable outputs. To solve this problem, we propose Probabilistic PIT (Prob-PIT) which considers the output-label permutation as a discrete latent random variable with a uniform prior distribution. Prob-PIT defines a log-likelihood function based on the prior distributions and the separation errors of all permutations; it trains the speech separation networks by maximizing the log-likelihood function. Prob-PIT can be easily implemented by replacing the minimum function of PIT with a soft-minimum function. We evaluate our approach for speech separation on both TIMIT and CHiME datasets. The results show that the proposed method significantly outperforms PIT in terms of Signal to Distortion Ratio and Signal to Interference Ratio.
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