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Register a new userImproved Breath Phase and Continuous Adventitious Sound Detection in Lung and Tracheal Sound Using Mixed Set Training and Domain Adaptation
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Added by
Chien-Wen Huang
Publication date
2021
fields
Informatics Engineering
and research's language is
English
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Previously, we established a lung sound database, HF_Lung_V2 and proposed convolutional bidirectional gated recurrent unit (CNN-BiGRU) models with adequate ability for inhalation, exhalation, continuous adventitious sound (CAS), and discontinuous adventitious sound detection in the lung sound. In this study, we proceeded to build a tracheal sound database, HF_Tracheal_V1, containing 11107 of 15-second tracheal sound recordings, 23087 inhalation labels, 16728 exhalation labels, and 6874 CAS labels. The tracheal sound in HF_Tracheal_V1 and the lung sound in HF_Lung_V2 were either combined or used alone to train the CNN-BiGRU models for respective lung and tracheal sound analysis. Different training strategies were investigated and compared: (1) using full training (training from scratch) to train the lung sound models using lung sound alone and train the tracheal sound models using tracheal sound alone, (2) using a mixed set that contains both the lung and tracheal sound to train the models, and (3) using domain adaptation that finetuned the pre-trained lung sound models with the tracheal sound data and vice versa. Results showed that the models trained only by lung sound performed poorly in the tracheal sound analysis and vice versa. However, the mixed set training and domain adaptation can improve the performance of exhalation and CAS detection in the lung sound, and inhalation, exhalation, and CAS detection in the tracheal sound compared to positive controls (lung models trained only by lung sound and vice versa). Especially, a model derived from the mixed set training prevails in the situation of killing two birds with one stone.
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We previously established a large lung sound database, HF_Lung_V2 (Lung_V2). We trained convolutional-bidirectional gated recurrent unit (CNN-BiGRU) networks for detecting inhalation, exhalation, continuous adventitious sound (CAS) and discontinuous adventitious sound at the recording level on the basis of Lung_V2. However, the performance of CAS detection was poor due to many reasons, one of which is the highly diversified CAS patterns. To make the original CNN-BiGRU model learn the CAS patterns more effectively and not cause too much computing burden, three strategies involving minimal modifications of the network architecture of the CNN layers were investigated: (1) making the CNN layers a bit deeper by using the residual blocks, (2) making the CNN layers a bit wider by increasing the number of CNN kernels, and (3) separating the feature input into multiple paths (the model was denoted by Multi-path CNN-BiGRU). The performance of CAS segment and event detection were evaluated. Results showed that improvement in CAS detection was observed among all the proposed architecture-modified models. The F1 score for CAS event detection of the proposed models increased from 0.445 to 0.491-0.530, which was deemed significant. However, the Multi-path CNN-BiGRU model outperformed the other models in terms of the number of winning titles (five) in total nine evaluation metrics. In addition, the Multi-path CNN-BiGRU model did not cause extra computing burden (0.97-fold inference time) compared to the original CNN-BiGRU model. Conclusively, the Multi-path CNN layers can efficiently improve the effectiveness of feature extraction and subsequently result in better CAS detection.
A reliable, remote, and continuous real-time respiratory sound monitor with automated respiratory sound analysis ability is urgently required in many clinical scenarios-such as in monitoring disease progression of coronavirus disease 2019-to replace conventional auscultation with a handheld stethoscope. However, a robust computerized respiratory sound analysis algorithm has not yet been validated in practical applications. In this study, we developed a lung sound database (HF_Lung_V1) comprising 9,765 audio files of lung sounds (duration of 15 s each), 34,095 inhalation labels, 18,349 exhalation labels, 13,883 continuous adventitious sound (CAS) labels (comprising 8,457 wheeze labels, 686 stridor labels, and 4,740 rhonchi labels), and 15,606 discontinuous adventitious sound labels (all crackles). We conducted benchmark tests for long short-term memory (LSTM), gated recurrent unit (GRU), bidirectional LSTM (BiLSTM), bidirectional GRU (BiGRU), convolutional neural network (CNN)-LSTM, CNN-GRU, CNN-BiLSTM, and CNN-BiGRU models for breath phase detection and adventitious sound detection. We also conducted a performance comparison between the LSTM-based and GRU-based models, between unidirectional and bidirectional models, and between models with and without a CNN. The results revealed that these models exhibited adequate performance in lung sound analysis. The GRU-based models outperformed, in terms of F1 scores and areas under the receiver operating characteristic curves, the LSTM-based models in most of the defined tasks. Furthermore, all bidirectional models outperformed their unidirectional counterparts. Finally, the addition of a CNN improved the accuracy of lung sound analysis, especially in the CAS detection tasks.
An anomalous sound detection system to detect unknown anomalous sounds usually needs to be built using only normal sound data. Moreover, it is desirable to improve the system by effectively using a small amount of anomalous sound data, which will be accumulated through the systems operation. As one of the methods to meet these requirements, we focus on a binary classification model that is developed by using not only normal data but also outlier data in the other domains as pseudo-anomalous sound data, which can be easily updated by using anomalous data. In this paper, we implement a new loss function based on metric learning to learn the distance relationship from each class centroid in feature space for the binary classification model. The proposed multi-task learning of the binary classification and the metric learning makes it possible to build the feature space where the within-class variance is minimized and the between-class variance is maximized while keeping normal and anomalous classes linearly separable. We also investigate the effectiveness of additionally using anomalous sound data for further improving the binary classification model. Our results showed that multi-task learning using binary classification and metric learning to consider the distance from each class centroid in the feature space is effective, and performance can be significantly improved by using even a small amount of anomalous data during training.
Sound event detection is an important facet of audio tagging that aims to identify sounds of interest and define both the sound category and time boundaries for each sound event in a continuous recording. With advances in deep neural networks, there has been tremendous improvement in the performance of sound event detection systems, although at the expense of costly data collection and labeling efforts. In fact, current state-of-the-art methods employ supervised training methods that leverage large amounts of data samples and corresponding labels in order to facilitate identification of sound category and time stamps of events. As an alternative, the current study proposes a semi-supervised method for generating pseudo-labels from unsupervised data using a student-teacher scheme that balances self-training and cross-training. Additionally, this paper explores post-processing which extracts sound intervals from network prediction, for further improvement in sound event detection performance. The proposed approach is evaluated on sound event detection task for the DCASE2020 challenge. The results of these methods on both validation and public evaluation sets of DESED database show significant improvement compared to the state-of-the art systems in semi-supervised learning.
Neural audio synthesis is an actively researched topic, having yielded a wide range of techniques that leverages machine learning architectures. Google Magenta elaborated a novel approach called Differential Digital Signal Processing (DDSP) that incorporates deep neural networks with preconditioned digital signal processing techniques, reaching state-of-the-art results especially in timbre transfer applications. However, most of these techniques, including the DDSP, are generally not applicable in real-time constraints, making them ineligible in a musical workflow. In this paper, we present a real-time implementation of the DDSP library embedded in a virtual synthesizer as a plug-in that can be used in a Digital Audio Workstation. We focused on timbre transfer from learned representations of real instruments to arbitrary sound inputs as well as controlling these models by MIDI. Furthermore, we developed a GUI for intuitive high-level controls which can be used for post-processing and manipulating the parameters estimated by the neural network. We have conducted a user experience test with seven participants online. The results indicated that our users found the interface appealing, easy to understand, and worth exploring further. At the same time, we have identified issues in the timbre transfer quality, in some components we did not implement, and in installation and distribution of our plugin. The next iteration of our design will address these issues. Our real-time MATLAB and JUCE implementations are available at https://github.com/SMC704/juce-ddsp and https://github.com/SMC704/matlab-ddsp , respectively.
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