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Register a new userFederated Semi-supervised Medical Image Classification via Inter-client Relation Matching
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Added by
Quande Liu
Publication date
2021
fields
Informatics Engineering
and research's language is
English
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Federated learning (FL) has emerged with increasing popularity to collaborate distributed medical institutions for training deep networks. However, despite existing FL algorithms only allow the supervised training setting, most hospitals in realistic usually cannot afford the intricate data labeling due to absence of budget or expertise. This paper studies a practical yet challenging FL problem, named textit{Federated Semi-supervised Learning} (FSSL), which aims to learn a federated model by jointly utilizing the data from both labeled and unlabeled clients (i.e., hospitals). We present a novel approach for this problem, which improves over traditional consistency regularization mechanism with a new inter-client relation matching scheme. The proposed learning scheme explicitly connects the learning across labeled and unlabeled clients by aligning their extracted disease relationships, thereby mitigating the deficiency of task knowledge at unlabeled clients and promoting discriminative information from unlabeled samples. We validate our method on two large-scale medical image classification datasets. The effectiveness of our method has been demonstrated with the clear improvements over state-of-the-arts as well as the thorough ablation analysis on both tasksfootnote{Code will be made available at url{https://github.com/liuquande/FedIRM}}.
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Training deep neural networks usually requires a large amount of labeled data to obtain good performance. However, in medical image analysis, obtaining high-quality labels for the data is laborious and expensive, as accurately annotating medical images demands expertise knowledge of the clinicians. In this paper, we present a novel relation-driven semi-supervised framework for medical image classification. It is a consistency-based method which exploits the unlabeled data by encouraging the prediction consistency of given input under perturbations, and leverages a self-ensembling model to produce high-quality consistency targets for the unlabeled data. Considering that human diagnosis often refers to previous analogous cases to make reliable decisions, we introduce a novel sample relation consistency (SRC) paradigm to effectively exploit unlabeled data by modeling the relationship information among different samples. Superior to existing consistency-based methods which simply enforce consistency of individual predictions, our framework explicitly enforces the consistency of semantic relation among different samples under perturbations, encouraging the model to explore extra semantic information from unlabeled data. We have conducted extensive experiments to evaluate our method on two public benchmark medical image classification datasets, i.e.,skin lesion diagnosis with ISIC 2018 challenge and thorax disease classification with ChestX-ray14. Our method outperforms many state-of-the-art semi-supervised learning methods on both single-label and multi-label image classification scenarios.
The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a high-performing FSS model still requires sufficient pixel-level annotated classes for training to avoid overfitting, which leads to its performance bottleneck in medical image segmentation due to the unmet need for annotations. Thus, semi-supervised FSS for medical images is accordingly proposed to utilize unlabeled data for further performance improvement. Nevertheless, existing semi-supervised FSS methods has two obvious defects: (1) neglecting the relationship between the labeled and unlabeled data; (2) using unlabeled data directly for end-to-end training leads to degenerated representation learning. To address these problems, we propose a novel semi-supervised FSS framework for medical image segmentation. The proposed framework employs Poisson learning for modeling data relationship and propagating supervision signals, and Spatial Consistency Calibration for encouraging the model to learn more coherent representations. In this process, unlabeled samples do not involve in end-to-end training, but provide supervisory information for query image segmentation through graph-based learning. We conduct extensive experiments on three medical image segmentation datasets (i.e. ISIC skin lesion segmentation, abdominal organs segmentation for MRI and abdominal organs segmentation for CT) to demonstrate the state-of-the-art performance and broad applicability of the proposed framework.
Consistency regularization is a technique for semi-supervised learning that underlies a number of strong results for classification with few labeled data. It works by encouraging a learned model to be robust to perturbations on unlabeled data. Here, we present a novel mask-based augmentation method called CowMask. Using it to provide perturbations for semi-supervised consistency regularization, we achieve a state-of-the-art result on ImageNet with 10% labeled data, with a top-5 error of 8.76% and top-1 error of 26.06%. Moreover, we do so with a method that is much simpler than many alternatives. We further investigate the behavior of CowMask for semi-supervised learning by running many smaller scale experiments on the SVHN, CIFAR-10 and CIFAR-100 data sets, where we achieve results competitive with the state of the art, indicating that CowMask is widely applicable. We open source our code at https://github.com/google-research/google-research/tree/master/milking_cowmask
Consistency training, which exploits both supervised and unsupervised learning with different augmentations on image, is an effective method of utilizing unlabeled data in semi-supervised learning (SSL) manner. Here, we present another version of the method with Grad-CAM consistency loss, so it can be utilized in training model with better generalization and adjustability. We show that our method improved the baseline ResNet model with at most 1.44 % and 0.31 $pm$ 0.59 %p accuracy improvement on average with CIFAR-10 dataset. We conducted ablation study comparing to using only psuedo-label for consistency training. Also, we argue that our method can adjust in different environments when targeted to different units in the model. The code is available: https://github.com/gimme1dollar/gradcam-consistency-semi-sup.
Deep learning has demonstrated significant improvements in medical image segmentation using a sufficiently large amount of training data with manual labels. Acquiring well-representative labels requires expert knowledge and exhaustive labors. In this paper, we aim to boost the performance of semi-supervised learning for medical image segmentation with limited labels using a self-ensembling contrastive learning technique. To this end, we propose to train an encoder-decoder network at image-level with small amounts of labeled images, and more importantly, we learn latent representations directly at feature-level by imposing contrastive loss on unlabeled images. This method strengthens intra-class compactness and inter-class separability, so as to get a better pixel classifier. Moreover, we devise a student encoder for online learning and an exponential moving average version of it, called teacher encoder, to improve the performance iteratively in a self-ensembling manner. To construct contrastive samples with unlabeled images, two sampling strategies that exploit structure similarity across medical images and utilize pseudo-labels for construction, termed region-aware and anatomical-aware contrastive sampling, are investigated. We conduct extensive experiments on an MRI and a CT segmentation dataset and demonstrate that in a limited label setting, the proposed method achieves state-of-the-art performance. Moreover, the anatomical-aware strategy that prepares contrastive samples on-the-fly using pseudo-labels realizes better contrastive regularization on feature representations.
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