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Register a new userSemi-supervised Medical Image Classification with Relation-driven Self-ensembling Model
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Added by
Quande Liu
Publication date
2020
fields
Informatics Engineering
and research's language is
English
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Training deep neural networks usually requires a large amount of labeled data to obtain good performance. However, in medical image analysis, obtaining high-quality labels for the data is laborious and expensive, as accurately annotating medical images demands expertise knowledge of the clinicians. In this paper, we present a novel relation-driven semi-supervised framework for medical image classification. It is a consistency-based method which exploits the unlabeled data by encouraging the prediction consistency of given input under perturbations, and leverages a self-ensembling model to produce high-quality consistency targets for the unlabeled data. Considering that human diagnosis often refers to previous analogous cases to make reliable decisions, we introduce a novel sample relation consistency (SRC) paradigm to effectively exploit unlabeled data by modeling the relationship information among different samples. Superior to existing consistency-based methods which simply enforce consistency of individual predictions, our framework explicitly enforces the consistency of semantic relation among different samples under perturbations, encouraging the model to explore extra semantic information from unlabeled data. We have conducted extensive experiments to evaluate our method on two public benchmark medical image classification datasets, i.e.,skin lesion diagnosis with ISIC 2018 challenge and thorax disease classification with ChestX-ray14. Our method outperforms many state-of-the-art semi-supervised learning methods on both single-label and multi-label image classification scenarios.
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Deep learning has demonstrated significant improvements in medical image segmentation using a sufficiently large amount of training data with manual labels. Acquiring well-representative labels requires expert knowledge and exhaustive labors. In this paper, we aim to boost the performance of semi-supervised learning for medical image segmentation with limited labels using a self-ensembling contrastive learning technique. To this end, we propose to train an encoder-decoder network at image-level with small amounts of labeled images, and more importantly, we learn latent representations directly at feature-level by imposing contrastive loss on unlabeled images. This method strengthens intra-class compactness and inter-class separability, so as to get a better pixel classifier. Moreover, we devise a student encoder for online learning and an exponential moving average version of it, called teacher encoder, to improve the performance iteratively in a self-ensembling manner. To construct contrastive samples with unlabeled images, two sampling strategies that exploit structure similarity across medical images and utilize pseudo-labels for construction, termed region-aware and anatomical-aware contrastive sampling, are investigated. We conduct extensive experiments on an MRI and a CT segmentation dataset and demonstrate that in a limited label setting, the proposed method achieves state-of-the-art performance. Moreover, the anatomical-aware strategy that prepares contrastive samples on-the-fly using pseudo-labels realizes better contrastive regularization on feature representations.
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This paper focuses on Semi-Supervised Object Detection (SSOD). Knowledge Distillation (KD) has been widely used for semi-supervised image classification. However, adapting these methods for SSOD has the following obstacles. (1) The teacher model serves a dual role as a teacher and a student, such that the teacher predictions on unlabeled images may be very close to those of student, which limits the upper-bound of the student. (2) The class imbalance issue in SSOD hinders an efficient knowledge transfer from teacher to student. To address these problems, we propose a novel method Temporal Self-Ensembling Teacher (TSE-T) for SSOD. Differently from previous KD based methods, we devise a temporally evolved teacher model. First, our teacher model ensembles its temporal predictions for unlabeled images under stochastic perturbations. Second, our teacher model ensembles its temporal model weights with the student model weights by an exponential moving average (EMA) which allows the teacher gradually learn from the student. These self-ensembling strategies increase data and model diversity, thus improving teacher predictions on unlabeled images. Finally, we use focal loss to formulate consistency regularization term to handle the data imbalance problem, which is a more efficient manner to utilize the useful information from unlabeled images than a simple hard-thresholding method which solely preserves confident predictions. Evaluated on the widely used VOC and COCO benchmarks, the mAP of our method has achieved 80.73% and 40.52% on the VOC2007 test set and the COCO2014 minval5k set respectively, which outperforms a strong fully-supervised detector by 2.37% and 1.49%. Furthermore, our method sets the new state-of-the-art in SSOD on VOC2007 test set which outperforms the baseline SSOD method by 1.44%. The source code of this work is publicly available at http://github.com/syangdong/tse-t.
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