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Confocal super-resolution microscopy based on a spatial mode sorter

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 Added by Yiyu Zhou
 Publication date 2021
and research's language is English




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Spatial resolution is one of the most important specifications of an imaging system. Recent results in quantum parameter estimation theory reveal that an arbitrarily small distance between two incoherent point sources can always be efficiently determined through the use of a spatial mode sorter. However, extending this procedure to a general object consisting of many incoherent point sources remains challenging, due to the intrinsic complexity of multi-parameter estimation problems. Here, we generalize the Richardson-Lucy (RL) deconvolution algorithm to address this challenge. We simulate its application to an incoherent confocal microscope, with a Zernike spatial mode sorter replacing the pinhole used in a conventional confocal microscope. We test different spatially incoherent objects of arbitrary geometry, and we find that the resolution enhancement of sorter-based microscopy is on average over 30% higher than that of a conventional confocal microscope using the standard RL deconvolution algorithm. Our method could potentially be used in diverse applications such as fluorescence microscopy and astronomical imaging.



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122 - Dongzhi Fu , Yiyu Zhou , Rui Qi 2018
The transverse structure of light is recognized as a resource that can be used to encode information onto photons and has been shown to be useful to enhance communication capacity as well as resolve point sources in superresolution imaging. The Laguerre-Gaussian (LG) modes form a complete and orthonormal basis set and are described by a radial index p and an orbital angular momentum (OAM) index l. Earlier works have shown how to build a sorter for the radial index p or/and the OAM index l of LG modes, but a scalable and dedicated LG mode sorter which simultaneous determinate p and l is immature. Here we propose and experimentally demonstrate a scheme to accomplish complete LG mode sorting, which consists of a novel, robust radial mode sorter that can be used to couple radial modes to polarizations, an l-dependent phase shifter and an OAM mode sorter. Our scheme is in principle efficient, scalable, and crosstalk-free, and therefore has potential for applications in optical communications, quantum information technology, superresolution imaging, and fiber optics.
One of the main characteristics of optical imaging systems is the spatial resolution, which is restricted by the diffraction limit to approximately half the wavelength of the incident light. Along with the recently developed classical super-resolution techniques, which aim at breaking the diffraction limit in classical systems, there is a class of quantum super-resolution techniques which leverage the non-classical nature of the optical signals radiated by quantum emitters, the so-called antibunching super-resolution microscopy. This approach can ensure a factor of $sqrt{n}$ improvement in the spatial resolution by measuring the n-th order autocorrelation function. The main bottleneck of the antibunching super-resolution microscopy is the time-consuming acquisition of multi-photon event histograms. We present a machine learning-assisted approach for the realization of rapid antibunching super-resolution imaging and demonstrate 12 times speed-up compared to conventional, fitting-based autocorrelation measurements. The developed framework paves the way to the practical realization of scalable quantum super-resolution imaging devices that can be compatible with various types of quantum emitters.
Raman microscopy is a valuable tool for detecting physical and chemical properties of a sample material. When probing nanomaterials or nanocomposites the spatial resolution of Raman microscopy is not always adequate as it is limited by the optical diffraction limit. Numerical post-processing with super-resolution algorithms provides a means to enhance resolution and can be straightforwardly applied. The aim of this work is to present interior-point least squares (IPLS) as a powerful tool for super-resolution in Raman imaging through constrained optimisation. IPLSs potential for super-resolution is illustrated on numerically generated test images. Its resolving power is demonstrated on Raman spectroscopic data of a polymer nanowire sample. Comparison to AFM data of the same sample substantiates that the presented method is a promising technique for analysing nanomaterial samples.
The Hermite-Gaussian (HG) modes, sometimes also referred to as transverse electromagnetic modes in free space, form a complete and orthonormal basis that have been extensively used to describe optical fields. In addition, these modes have been shown to be helpful to enhance information capacity of optical communications as well as to achieve super-resolution imaging in microscopy. Here we propose and present the realization of an efficient, robust mode sorter that can sort a large number of HG modes based on the relation between HG modes and Laguerre-Gaussian (LG) modes. We experimentally demonstrate the sorting of 16 HG modes, and our method can be readily extended to a higher-dimensional state space in a straightforward manner. We expect that our demonstration will have direct applications in a variety of fields including fiber optics, classical and quantum communications, as well as super-resolution imaging.
The dimension of the state space for information encoding offered by the transverse structure of light is usually limited by the finite size of apertures. The widely used orbital angular momentum (OAM) number of Laguerre-Gaussian (LG) modes in free-space communications cannot achieve the theoretical maximum transmission capacity unless the radial degree of freedom is multiplexed into the protocol. While the methodology to sort the radial quantum number has been developed, the application of radial modes in quantum communications requires an additional ability to efficiently measure the superposition of LG modes in the mutually unbiased basis. Here we develop and implement a generic mode sorter that is capable of sorting the superposition of LG modes through the use of a mode converter. As a consequence, we demonstrate an 8-dimensional quantum key distribution experiment involving all three transverse degrees of freedom: spin, azimuthal, and radial quantum numbers of photons. Our protocol presents an important step towards the goal of reaching the capacity limit of a free-space link and can be useful to other applications that involve spatial modes of photons.
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