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Register a new userTowards Autonomous Eye Surgery by Combining Deep Imitation Learning with Optimal Control
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Added by
Ji Woong Kim
Publication date
2020
fields
Informatics Engineering
and research's language is
English
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During retinal microsurgery, precise manipulation of the delicate retinal tissue is required for positive surgical outcome. However, accurate manipulation and navigation of surgical tools remain difficult due to a constrained workspace and the top-down view during the surgery, which limits the surgeons ability to estimate depth. To alleviate such difficulty, we propose to automate the tool-navigation task by learning to predict relative goal position on the retinal surface from the current tool-tip position. Given an estimated target on the retina, we generate an optimal trajectory leading to the predicted goal while imposing safety-related physical constraints aimed to minimize tissue damage. As an extended task, we generate goal predictions to various points across the retina to localize eye geometry and further generate safe trajectories within the estimated confines. Through experiments in both simulation and with several eye phantoms, we demonstrate that our framework can permit navigation to various points on the retina within 0.089mm and 0.118mm in xy error which is less than the humans surgeon mean tremor at the tool-tip of 0.180mm. All safety constraints were fulfilled and the algorithm was robust to previously unseen eyes as well as unseen objects in the scene. Live video demonstration is available here: https://youtu.be/n5j5jCCelXk
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While robot learning has demonstrated promising results for enabling robots to automatically acquire new skills, a critical challenge in deploying learning-based systems is scale: acquiring enough data for the robot to effectively generalize broadly. Imitation learning, in particular, has remained a stable and powerful approach for robot learning, but critically relies on expert operators for data collection. In this work, we target this challenge, aiming to build an imitation learning system that can continuously improve through autonomous data collection, while simultaneously avoiding the explicit use of reinforcement learning, to maintain the stability, simplicity, and scalability of supervised imitation. To accomplish this, we cast the problem of imitation with autonomous improvement into a multi-task setting. We utilize the insight that, in a multi-task setting, a failed attempt at one task might represent a successful attempt at another task. This allows us to leverage the robots own trials as demonstrations for tasks other than the one that the robot actually attempted. Using an initial dataset of multi-task demonstration data, the robot autonomously collects trials which are only sparsely labeled with a binary indication of whether the trial accomplished any useful task or not. We then embed the trials into a learned latent space of tasks, trained using only the initial demonstration dataset, to draw similarities between various trials, enabling the robot to achieve one-shot generalization to new tasks. In contrast to prior imitation learning approaches, our method can autonomously collect data with sparse supervision for continuous improvement, and in contrast to reinforcement learning algorithms, our method can effectively improve from sparse, task-agnostic reward signals.
Ophthalmic microsurgery is known to be a challenging operation, which requires very precise and dexterous manipulation. Image guided robot-assisted surgery (RAS) is a promising solution that brings significant improvements in outcomes and reduces the physical limitations of human surgeons. However, this technology must be further developed before it can be routinely used in clinics. One of the problems is the lack of proper calibration between the robotic manipulator and appropriate imaging device. In this work, we developed a flexible framework for hand-eye calibration of an ophthalmic robot with a microscope-integrated Optical Coherence Tomography (MIOCT) without any markers. The proposed method consists of three main steps: a) we estimate the OCT calibration parameters; b) with micro-scale displacements controlled by the robot, we detect and segment the needle tip in 3D-OCT volume; c) we find the transformation between the coordinate system of the OCT camera and the coordinate system of the robot. We verified the capability of our framework in ex-vivo pig eye experiments and compared the results with a reference method (marker-based). In all experiments, our method showed a small difference from the marker based method, with a mean calibration error of 9.2 $mu$m and 7.0 $mu$m, respectively. Additionally, the noise test shows the robustness of the proposed method.
Vitreoretinal surgery is challenging even for expert surgeons owing to the delicate target tissues and the diminutive 7-mm-diameter workspace in the retina. In addition to improved dexterity and accuracy, robot assistance allows for (partial) task automation. In this work, we propose a strategy to automate the motion of the light guide with respect to the surgical instrument. This automation allows the instruments shadow to always be inside the microscopic view, which is an important cue for the accurate positioning of the instrument in the retina. We show simulations and experiments demonstrating that the proposed strategy is effective in a 700-point grid in the retina of a surgical phantom.
We develop optimal control strategies for Autonomous Vehicles (AVs) that are required to meet complex specifications imposed by traffic laws and cultural expectations of reasonable driving behavior. We formulate these specifications as rules, and specify their priorities by constructing a priority structure. We propose a recursive framework, in which the satisfaction of the rules in the priority structure are iteratively relaxed based on their priorities. Central to this framework is an optimal control problem, where convergence to desired states is achieved using Control Lyapunov Functions (CLFs), and safety is enforced through Control Barrier Functions (CBFs). We also show how the proposed framework can be used for after-the-fact, pass / fail evaluation of trajectories - a given trajectory is rejected if we can find a controller producing a trajectory that leads to less violation of the rule priority structure. We present case studies with multiple driving scenarios to demonstrate the effectiveness of the proposed framework.
Autonomous driving in multi-agent and dynamic traffic scenarios is challenging, where the behaviors of other road agents are uncertain and hard to model explicitly, and the ego-vehicle should apply complicated negotiation skills with them to achieve both safe and efficient driving in various settings, such as giving way, merging and taking turns. Traditional planning methods are largely rule-based and scale poorly in these complex dynamic scenarios, often leading to reactive or even overly conservative behaviors. Therefore, they require tedious human efforts to maintain workability. Recently, deep learning-based methods have shown promising results with better generalization capability but less hand engineering effort. However, they are either implemented with supervised imitation learning (IL) that suffers from the dataset bias and distribution mismatch problems, or trained with deep reinforcement learning (DRL) but focus on one specific traffic scenario. In this work, we propose DQ-GAT to achieve scalable and proactive autonomous driving, where graph attention-based networks are used to implicitly model interactions, and asynchronous deep Q-learning is employed to train the network end-to-end in an unsupervised manner. Extensive experiments through a high-fidelity driving simulation show that our method can better trade-off safety and efficiency in both seen and unseen scenarios, achieving higher goal success rates than the baselines (at most 4.7$times$) with comparable task completion time. Demonstration videos are available at https://caipeide.github.io/dq-gat/.
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