No Arabic abstract
Accounting for sex and gender characteristics is a complex, structural challenge in social science research. While other methodology papers consider issues surrounding appropriate measurement, we consider how gender and sex impact adjustments for non-response patterns in sampling and survey estimates. We consider the problem of survey adjustment arising from the recent push toward measuring sex or gender as a non-binary construct. This is challenging not only in that response categories differ between sex and gender measurement, but also in that both of these attributes are potentially multidimensional. In this manuscript we reflect on similarities to measuring race/ethnicity before considering the ethical and statistical implications of the options available to us. We do not conclude with a single best recommendation but rather an awareness of the complexity of the issues surrounding this challenge and the benefits and weaknesses of different approaches.
Strikingly few Nobel laureates within medicine, natural and social sciences are women. Although it is obvious that there are fewer women researchers within these fields, does this gender ratio still fully account for the low number of female Nobel laureates? We examine whether women are awarded the Nobel Prizes less often than the gender ratio suggests. Based on historical data across four scientific fields and a Bayesian hierarchical model, we quantify any possible bias. The model reveals, with exceedingly large confidence, that indeed women are strongly under-represented among Nobel laureates across all disciplines examined.
The sex ratio at birth (SRB) in India has been reported imbalanced since the 1970s. Previous studies have shown a great variation in the SRB across geographic locations in India till 2016. As one of the most populous countries and in view of its great regional heterogeneity, it is crucial to produce probabilistic projections for the SRB in India at state level for the purpose of population projection and policy planning. In this paper, we implement a Bayesian hierarchical time series model to project SRB in India by state. We generate SRB probabilistic projections from 2017 to 2030 for 29 States and Union Territories (UTs) in India, and present results in 21 States/UTs with data from the Sample Registration System. Our analysis takes into account two state-specific factors that contribute to sex-selective abortion and resulting sex imbalances at birth: intensity of son preference and fertility squeeze. We project that the largest contribution to female births deficits is in Uttar Pradesh, with cumulative number of missing female births projected to be 2.0 (95% credible interval [1.9; 2.2]) million from 2017 to 2030. The total female birth deficits during 2017-2030 for the whole India is projected to be 6.8 [6.6; 7.0] million.
Prior to adjustment, accounting conditions between national accounts data sets are frequently violated. Benchmarking is the procedure used by economic agencies to make such data sets consistent. It typically involves adjusting a high frequency time series (e.g. quarterly data) so it becomes consistent with a lower frequency version (e.g. annual data). Various methods have been developed to approach this problem of inconsistency between data sets. This paper introduces a new statistical procedure; namely wavelet benchmarking. Wavelet properties allow high and low frequency processes to be jointly analysed and we show that benchmarking can be formulated and approached succinctly in the wavelet domain. Furthermore the time and frequency localisation properties of wavelets are ideal for handling more complicated benchmarking problems. The versatility of the procedure is demonstrated using simulation studies where we provide evidence showing it substantially outperforms currently used methods. Finally, we apply this novel method of wavelet benchmarking to official Office of National Statistics (ONS) data.
Estimation of model parameters of computer simulators, also known as calibration, is an important topic in many engineering applications. In this paper, we consider the calibration of computer model parameters with the help of engineering design knowledge. We introduce the concept of sensible (calibration) variables. Sensible variables are model parameters which are sensitive in the engineering modeling, and whose optimal values differ from the engineering design values.We propose an effective calibration method to identify and adjust the sensible variables with limited physical experimental data. The methodology is applied to a composite fuselage simulation problem.
In biomedical studies it is of substantial interest to develop risk prediction scores using high-dimensional data such as gene expression data for clinical endpoints that are subject to censoring. In the presence of well-established clinical risk factors, investigators often prefer a procedure that also adjusts for these clinical variables. While accelerated failure time (AFT) models are a useful tool for the analysis of censored outcome data, it assumes that covariate effects on the logarithm of time-to-event are linear, which is often unrealistic in practice. We propose to build risk prediction scores through regularized rank estimation in partly linear AFT models, where high-dimensional data such as gene expression data are modeled linearly and important clinical variables are modeled nonlinearly using penalized regression splines. We show through simulation studies that our model has better operating characteristics compared to several existing models. In particular, we show that there is a nonnegligible effect on prediction as well as feature selection when nonlinear clinical effects are misspecified as linear. This work is motivated by a recent prostate cancer study, where investigators collected gene expression data along with established prognostic clinical variables and the primary endpoint is time to prostate cancer recurrence.