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Register a new userFew-Shot Anomaly Detection for Polyp Frames from Colonoscopy
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Added by
Yu Tian
Publication date
2020
fields
Informatics Engineering
and research's language is
English
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Anomaly detection methods generally target the learning of a normal image distribution (i.e., inliers showing healthy cases) and during testing, samples relatively far from the learned distribution are classified as anomalies (i.e., outliers showing disease cases). These approaches tend to be sensitive to outliers that lie relatively close to inliers (e.g., a colonoscopy image with a small polyp). In this paper, we address the inappropriate sensitivity to outliers by also learning from inliers. We propose a new few-shot anomaly detection method based on an encoder trained to maximise the mutual information between feature embeddings and normal images, followed by a few-shot score inference network, trained with a large set of inliers and a substantially smaller set of outliers. We evaluate our proposed method on the clinical problem of detecting frames containing polyps from colonoscopy video sequences, where the training set has 13350 normal images (i.e., without polyps) and less than 100 abnormal images (i.e., with polyps). The results of our proposed model on this data set reveal a state-of-the-art detection result, while the performance based on different number of anomaly samples is relatively stable after approximately 40 abnormal training images.
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The automatic detection of frames containing polyps from a colonoscopy video sequence is an important first step for a fully automated colonoscopy analysis tool. Typically, such detection system is built using a large annotated data set of frames with and without polyps, which is expensive to be obtained. In this paper, we introduce a new system that detects frames containing polyps as anomalies from a distribution of frames from exams that do not contain any polyps. The system is trained using a one-class training set consisting of colonoscopy frames without polyps -- such training set is considerably less expensive to obtain, compared to the 2-class data set mentioned above. During inference, the system is only able to reconstruct frames without polyps, and when it tries to reconstruct a frame with polyp, it automatically removes (i.e., photoshop) it from the frame -- the difference between the input and reconstructed frames is used to detect frames with polyps. We name our proposed model as anomaly detection generative adversarial network (ADGAN), comprising a dual GAN with two generators and two discriminators. We show that our proposed approach achieves the state-of-the-art result on this data set, compared with recently proposed anomaly detection systems.
Differentiation of colorectal polyps is an important clinical examination. A computer-aided diagnosis system is required to assist accurate diagnosis from colonoscopy images. Most previous studies at-tempt to develop models for polyp differentiation using Narrow-Band Imaging (NBI) or other enhanced images. However, the wide range of these models applications for clinical work has been limited by the lagging of imaging techniques. Thus, we propose a novel framework based on a teacher-student architecture for the accurate colorectal polyp classification (CPC) through directly using white-light (WL) colonoscopy images in the examination. In practice, during training, the auxiliary NBI images are utilized to train a teacher network and guide the student network to acquire richer feature representation from WL images. The feature transfer is realized by domain alignment and contrastive learning. Eventually the final student network has the ability to extract aligned features from only WL images to facilitate the CPC task. Besides, we release the first public-available paired CPC dataset containing WL-NBI pairs for the alignment training. Quantitative and qualitative evaluation indicates that the proposed method outperforms the previous methods in CPC, improving the accuracy by 5.6%with very fast speed.
Colorectal cancer (CRC) is a common and lethal disease. Globally, CRC is the third most commonly diagnosed cancer in males and the second in females. For colorectal cancer, the best screening test available is the colonoscopy. During a colonoscopic procedure, a tiny camera at the tip of the endoscope generates a video of the internal mucosa of the colon. The video data are displayed on a monitor for the physician to examine the lining of the entire colon and check for colorectal polyps. Detection and removal of colorectal polyps are associated with a reduction in mortality from colorectal cancer. However, the miss rate of polyp detection during colonoscopy procedure is often high even for very experienced physicians. The reason lies in the high variation of polyp in terms of shape, size, textural, color and illumination. Though challenging, with the great advances in object detection techniques, automated polyp detection still demonstrates a great potential in reducing the false negative rate while maintaining a high precision. In this paper, we propose a novel anchor free polyp detector that can localize polyps without using predefined anchor boxes. To further strengthen the model, we leverage a Context Enhancement Module and Cosine Ground truth Projection. Our approach can respond in real time while achieving state-of-the-art performance with 99.36% precision and 96.44% recall.
Automatic colorectal polyp detection in colonoscopy video is a fundamental task, which has received a lot of attention. Manually annotating polyp region in a large scale video dataset is time-consuming and expensive, which limits the development of deep learning techniques. A compromise is to train the target model by using labeled images and infer on colonoscopy videos. However, there are several issues between the image-based training and video-based inference, including domain differences, lack of positive samples, and temporal smoothness. To address these issues, we propose an Image-video-joint polyp detection network (Ivy-Net) to address the domain gap between colonoscopy images from historical medical reports and real-time videos. In our Ivy-Net, a modified mixup is utilized to generate training data by combining the positive images and negative video frames at the pixel level, which could learn the domain adaptive representations and augment the positive samples. Simultaneously, a temporal coherence regularization (TCR) is proposed to introduce the smooth constraint on feature-level in adjacent frames and improve polyp detection by unlabeled colonoscopy videos. For evaluation, a new large colonoscopy polyp dataset is collected, which contains 3056 images from historical medical reports of 889 positive patients and 7.5-hour videos of 69 patients (28 positive). The experiments on the collected dataset demonstrate that our Ivy-Net achieves the state-of-the-art result on colonoscopy video.
We introduce Few-Shot Video Object Detection (FSVOD) with three important contributions: 1) a large-scale video dataset FSVOD-500 comprising of 500 classes with class-balanced videos in each category for few-shot learning; 2) a novel Tube Proposal Network (TPN) to generate high-quality video tube proposals to aggregate feature representation for the target video object; 3) a strategically improved Temporal Matching Network (TMN+) to match representative query tube features and supports with better discriminative ability. Our TPN and TMN+ are jointly and end-to-end trained. Extensive experiments demonstrate that our method produces significantly better detection results on two few-shot video object detection datasets compared to image-based methods and other naive video-based extensions. Codes and datasets will be released at https://github.com/fanq15/FewX.
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