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Register a new userMulti-task Learning via Adaptation to Similar Tasks for Mortality Prediction of Diverse Rare Diseases
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Mortality prediction of diverse rare diseases using electronic health record (EHR) data is a crucial task for intelligent healthcare. However, data insufficiency and the clinical diversity of rare diseases make it hard for directly training deep learning models on individual disease data or all the data from different diseases. Mortality prediction for these patients with different diseases can be viewed as a multi-task learning problem with insufficient data and large task number. But the tasks with little training data also make it hard to train task-specific modules in multi-task learning models. To address the challenges of data insufficiency and task diversity, we propose an initialization-sharing multi-task learning method (Ada-Sit) which learns the parameter initialization for fast adaptation to dynamically measured similar tasks. We use Ada-Sit to train long short-term memory networks (LSTM) based prediction models on longitudinal EHR data. And experimental results demonstrate that the proposed model is effective for mortality prediction of diverse rare diseases.
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Multi-task learning (MTL) can improve performance on a task by sharing representations with one or more related auxiliary-tasks. Usually, MTL-networks are trained on a composite loss function formed by a constant weighted combination of the separate task losses. In practice, constant loss weights lead to poor results for two reasons: (i) the relevance of the auxiliary tasks can gradually drift throughout the learning process; (ii) for mini-batch based optimisation, the optimal task weights vary significantly from one update to the next depending on mini-batch sample composition. We introduce HydaLearn, an intelligent weighting algorithm that connects main-task gain to the individual task gradients, in order to inform dynamic loss weighting at the mini-batch level, addressing i and ii. Using HydaLearn, we report performance increases on synthetic data, as well as on two supervised learning domains.
Although recent multi-task learning methods have shown to be effective in improving the generalization of deep neural networks, they should be used with caution for safety-critical applications, such as clinical risk prediction. This is because even if they achieve improved task-average performance, they may still yield degraded performance on individual tasks, which may be critical (e.g., prediction of mortality risk). Existing asymmetric multi-task learning methods tackle this negative transfer problem by performing knowledge transfer from tasks with low loss to tasks with high loss. However, using loss as a measure of reliability is risky since it could be a result of overfitting. In the case of time-series prediction tasks, knowledge learned for one task (e.g., predicting the sepsis onset) at a specific timestep may be useful for learning another task (e.g., prediction of mortality) at a later timestep, but lack of loss at each timestep makes it difficult to measure the reliability at each timestep. To capture such dynamically changing asymmetric relationships between tasks in time-series data, we propose a novel temporal asymmetric multi-task learning model that performs knowledge transfer from certain tasks/timesteps to relevant uncertain tasks, based on feature-level uncertainty. We validate our model on multiple clinical risk prediction tasks against various deep learning models for time-series prediction, which our model significantly outperforms, without any sign of negative transfer. Further qualitative analysis of learned knowledge graphs by clinicians shows that they are helpful in analyzing the predictions of the model. Our final code is available at https://github.com/anhtuan5696/TPAMTL.
Role-based learning holds the promise of achieving scalable multi-agent learning by decomposing complex tasks using roles. However, it is largely unclear how to efficiently discover such a set of roles. To solve this problem, we propose to first decompose joint action spaces into restricted role action spaces by clustering actions according to their effects on the environment and other agents. Learning a role selector based on action effects makes role discovery much easier because it forms a bi-level learning hierarchy -- the role selector searches in a smaller role space and at a lower temporal resolution, while role policies learn in significantly reduced primitive action-observation spaces. We further integrate information about action effects into the role policies to boost learning efficiency and policy generalization. By virtue of these advances, our method (1) outperforms the current state-of-the-art MARL algorithms on 10 of the 14 scenarios that comprise the challenging StarCraft II micromanagement benchmark and (2) achieves rapid transfer to new environments with three times the number of agents. Demonstrative videos are available at https://sites.google.com/view/rode-marl .
Some tasks, such as surface normals or single-view depth estimation, require per-pixel ground truth that is difficult to obtain on real images but easy to obtain on synthetic. However, models learned on synthetic images often do not generalize well to real images due to the domain shift. Our key idea to improve domain adaptation is to introduce a separate anchor task (such as facial landmarks) whose annotations can be obtained at no cost or are already available on both synthetic and real datasets. To further leverage the implicit relationship between the anchor and main tasks, we apply our freeze technique that learns the cross-task guidance on the source domain with the final network layers, and use it on the target domain. We evaluate our methods on surface normal estimation on two pairs of datasets (indoor scenes and faces) with two kinds of anchor tasks (semantic segmentation and facial landmarks). We show that blindly applying domain adaptation or training the auxiliary task on only one domain may hurt performance, while using anchor tasks on both domains is better behaved. Our freeze technique outperforms competing approaches, reaching performance in facial images on par with a recently popular surface normal estimation method using shape from shading domain knowledge.
Multi-task learning is a powerful method for solving multiple correlated tasks simultaneously. However, it is often impossible to find one single solution to optimize all the tasks, since different tasks might conflict with each other. Recently, a novel method is proposed to find one single Pareto optimal solution with good trade-off among different tasks by casting multi-task learning as multiobjective optimization. In this paper, we generalize this idea and propose a novel Pareto multi-task learning algorithm (Pareto MTL) to find a set of well-distributed Pareto solutions which can represent different trade-offs among different tasks. The proposed algorithm first formulates a multi-task learning problem as a multiobjective optimization problem, and then decomposes the multiobjective optimization problem into a set of constrained subproblems with different trade-off preferences. By solving these subproblems in parallel, Pareto MTL can find a set of well-representative Pareto optimal solutions with different trade-off among all tasks. Practitioners can easily select their preferred solution from these Pareto solutions, or use different trade-off solutions for different situations. Experimental results confirm that the proposed algorithm can generate well-representative solutions and outperform some state-of-the-art algorithms on many multi-task learning applications.
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