Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userSpatio-Temporal Graph Convolution for Resting-State fMRI Analysis
76
0
0.0
(
0
)
Ask ChatGPT about the research
No Arabic abstract
The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the functional dependency between different brain regions in a network or discard the information in the temporal dynamics of brain activity. To overcome those shortcomings, we propose to formulate functional connectivity networks within the context of spatio-temporal graphs. We train a spatio-temporal graph convolutional network (ST-GCN) on short sub-sequences of the BOLD time series to model the non-stationary nature of functional connectivity. Simultaneously, the model learns the importance of graph edges within ST-GCN to gain insight into the functional connectivities contributing to the prediction. In analyzing the rs-fMRI of the Human Connectome Project (HCP, N=1,091) and the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA, N=773), ST-GCN is significantly more accurate than common approaches in predicting gender and age based on BOLD signals. Furthermore, the brain regions and functional connections significantly contributing to the predictions of our model are important markers according to the neuroscience literature.
rate research
Read More
Long-range temporal coherence (LRTC) is quite common to dynamic systems and is fundamental to the system function. LRTC in the brain has been shown to be important to cognition. Assessing LRTC may provide critical information for understanding the potential underpinnings of brain organization, function, and cognition. To facilitate this overarching goal, we provide a method, which is named temporal coherence mapping (TCM), to explicitly quantify LRTC using resting state fMRI. TCM is based on correlation analysis of the transit states of the phase space reconstructed by temporal embedding. A few TCM properties were collected to measure LRTC, including the averaged correlation, anti-correlation, the ratio of correlation and anticorrelation, the mean coherent and incoherent duration, and the ratio between the coherent and incoherent time. TCM was first evaluated with simulations and then with the large Human Connectome Project data. Evaluation results showed that TCM metrics can successfully differentiate signals with different temporal coherence regardless of the parameters used to reconstruct the phase space. In human brain, TCM metrics except the ratio of the coherent/incoherent time showed high test-retest reproducibility; TCM metrics are related to age, sex, and total cognitive scores. In summary, TCM provides a first-of-its-kind tool to assess LRTC and the imbalance between coherence and incoherence; TCM properties are physiologically and cognitively meaningful.
Deep learning models are modern tools for spatio-temporal graph (STG) forecasting. Despite their effectiveness, they require large-scale datasets to achieve better performance and are vulnerable to noise perturbation. To alleviate these limitations, an intuitive idea is to use the popular data augmentation and contrastive learning techniques. However, existing graph contrastive learning methods cannot be directly applied to STG forecasting due to three reasons. First, we empirically discover that the forecasting task is unable to benefit from the pretrained representations derived from contrastive learning. Second, data augmentations that are used for defeating noise are less explored for STG data. Third, the semantic similarity of samples has been overlooked. In this paper, we propose a Spatio-Temporal Graph Contrastive Learning framework (STGCL) to tackle these issues. Specifically, we improve the performance by integrating the forecasting loss with an auxiliary contrastive loss rather than using a pretrained paradigm. We elaborate on four types of data augmentations, which disturb data in terms of graph structure, time domain, and frequency domain. We also extend the classic contrastive loss through a rule-based strategy that filters out the most semantically similar negatives. Our framework is evaluated across three real-world datasets and four state-of-the-art models. The consistent improvements demonstrate that STGCL can be used as an off-the-shelf plug-in for existing deep models.
We established a Spatio-Temporal Neural Network, namely STNN, to forecast the spread of the coronavirus COVID-19 outbreak worldwide in 2020. The basic structure of STNN is similar to the Recurrent Neural Network (RNN) incorporating with not only temporal data but also spatial features. Two improved STNN architectures, namely the STNN with Augmented Spatial States (STNN-A) and the STNN with Input Gate (STNN-I), are proposed, which ensure more predictability and flexibility. STNN and its variants can be trained using Stochastic Gradient Descent (SGD) algorithm and its improved variants (e.g., Adam, AdaGrad and RMSProp). Our STNN models are compared with several classical epidemic prediction models, including the fully-connected neural network (BPNN), and the recurrent neural network (RNN), the classical curve fitting models, as well as the SEIR dynamical system model. Numerical simulations demonstrate that STNN models outperform many others by providing more accurate fitting and prediction, and by handling both spatial and temporal data.
Research in deep learning models to forecast traffic intensities has gained great attention in recent years due to their capability to capture the complex spatio-temporal relationships within the traffic data. However, most state-of-the-art approaches have designed spatial-only (e.g. Graph Neural Networks) and temporal-only (e.g. Recurrent Neural Networks) modules to separately extract spatial and temporal features. However, we argue that it is less effective to extract the complex spatio-temporal relationship with such factorized modules. Besides, most existing works predict the traffic intensity of a particular time interval only based on the traffic data of the previous one hour of that day. And thereby ignores the repetitive daily/weekly pattern that may exist in the last hour of data. Therefore, we propose a Unified Spatio-Temporal Graph Convolution Network (USTGCN) for traffic forecasting that performs both spatial and temporal aggregation through direct information propagation across different timestamp nodes with the help of spectral graph convolution on a spatio-temporal graph. Furthermore, it captures historical daily patterns in previous days and current-day patterns in current-day traffic data. Finally, we validate our works effectiveness through experimental analysis, which shows that our model USTGCN can outperform state-of-the-art performances in three popular benchmark datasets from the Performance Measurement System (PeMS). Moreover, the training time is reduced significantly with our proposed USTGCN model.
Functional Magnetic Resonance Imaging (fMRI) is a non-invasive technique for studying brain activity. During an fMRI session, the subject executes a set of tasks (task-related fMRI study) or no tasks (resting-state fMRI), and a sequence of 3-D brain images is obtained for further analysis. In the course of fMRI, some sources of activation are caused by noise and artifacts. The removal of these sources is essential before the analysis of the brain activations. Deep Neural Network (DNN) architectures can be used for denoising and artifact removal. The main advantage of DNN models is the automatic learning of abstract and meaningful features, given the raw data. This work presents advanced DNN architectures for noise and artifact classification, using both spatial and temporal information in resting-state fMRI sessions. The highest performance is achieved by a voting schema using information from all the domains, with an average accuracy of over 98% and a very good balance between the metrics of sensitivity and specificity (98.5% and 97.5% respectively).
suggested questions
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
