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Register a new userFree-breathing Cardiovascular MRI Using a Plug-and-Play Method with Learned Denoiser
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Cardiac magnetic resonance imaging (CMR) is a noninvasive imaging modality that provides a comprehensive evaluation of the cardiovascular system. The clinical utility of CMR is hampered by long acquisition times, however. In this work, we propose and validate a plug-and-play (PnP) method for CMR reconstruction from undersampled multi-coil data. To fully exploit the rich image structure inherent in CMR, we pair the PnP framework with a deep learning (DL)-based denoiser that is trained using spatiotemporal patches from high-quality, breath-held cardiac cine images. The resulting PnP-DL method iterates over data consistency and denoising subroutines. We compare the reconstruction performance of PnP-DL to that of compressed sensing (CS) using eight breath-held and ten real-time (RT) free-breathing cardiac cine datasets. We find that, for breath-held datasets, PnP-DL offers more than one dB advantage over commonly used CS methods. For RT free-breathing datasets, where ground truth is not available, PnP-DL receives higher scores in qualitative evaluation. The results highlight the potential of PnP-DL to accelerate RT CMR.
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Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides excellent soft-tissue contrast without using ionizing radiation. MRIs clinical application may be limited by long data acquisition time; therefore, MR image reconstruction from highly under-sampled k-space data has been an active research area. Calibrationless MRI not only enables a higher acceleration rate but also increases flexibility for sampling pattern design. To leverage non-linear machine learning priors, we pair our High-dimensional Fast Convolutional Framework (HICU) with a plug-in denoiser and demonstrate its feasibility using 2D brain data.
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. Conventional MRI reconstruction methods for fast MRI acquisition mostly relied on different regularizers which represent analytical models of sparsity. However, recent data-driven methods based on deep learning has resulted in promising improvements in image reconstruction algorithms. In this paper, we propose a deep plug-and-play prior framework for parallel MRI reconstruction problems which utilize a deep neural network (DNN) as an advanced denoiser within an iterative method. This, in turn, enables rapid acquisition of MR images with improved image quality. The proposed method was compared with the reconstructions using the clinical gold standard GRAPPA method. Our results with undersampled data demonstrate that our method can deliver considerably higher quality images at high acceleration factors in comparison to clinical gold standard method for MRI reconstructions. Our proposed reconstruction enables an increase in acceleration factor, and a reduction in acquisition time while maintaining high image quality.
Plug-and-play priors (PnP) is an image reconstruction framework that uses an image denoiser as an imaging prior. Unlike traditional regularized inversion, PnP does not require the prior to be expressible in the form of a regularization function. This flexibility enables PnP algorithms to exploit the most effective image denoisers, leading to their state-of-the-art performance in various imaging tasks. In this paper, we propose a new denoiser scaling technique to explicitly control the amount of PnP regularization. Traditionally, the performance of PnP algorithms is controlled via intrinsic parameters of the denoiser related to the noise variance. However, many powerful denoisers, such as the ones based on convolutional neural networks (CNNs), do not have tunable parameters that would allow controlling their influence within PnP. To address this issue, we introduce a scaling parameter that adjusts the magnitude of the denoiser input and output. We theoretical justify the denoiser scaling from the perspectives of proximal optimization, statistical estimation, and consensus equilibrium. Finally, we provide numerical experiments demonstrating the ability of denoiser scaling to systematically improve the performance of PnP for denoising CNN priors that do not have explicitly tunable parameters.
We consider the reconstruction problem of video snapshot compressive imaging (SCI), which captures high-speed videos using a low-speed 2D sensor (detector). The underlying principle of SCI is to modulate sequential high-speed frames with different masks and then these encoded frames are integrated into a snapshot on the sensor and thus the sensor can be of low-speed. On one hand, video SCI enjoys the advantages of low-bandwidth, low-power and low-cost. On the other hand, applying SCI to large-scale problems (HD or UHD videos) in our daily life is still challenging and one of the bottlenecks lies in the reconstruction algorithm. Exiting algorithms are either too slow (iterative optimization algorithms) or not flexible to the encoding process (deep learning based end-to-end networks). In this paper, we develop fast and flexible algorithms for SCI based on the plug-and-play (PnP) framework. In addition to the PnP-ADMM method, we further propose the PnP-GAP (generalized alternating projection) algorithm with a lower computational workload. We first employ the image deep denoising priors to show that PnP can recover a UHD color video with 30 frames from a snapshot measurement. Since videos have strong temporal correlation, by employing the video deep denoising priors, we achieve a significant improvement in the results. Furthermore, we extend the proposed PnP algorithms to the color SCI system using mosaic sensors, where each pixel only captures the red, green or blue channels. A joint reconstruction and demosaicing paradigm is developed for flexible and high quality reconstruction of color video SCI systems. Extensive results on both simulation and real datasets verify the superiority of our proposed algorithm.
Snapshot compressive imaging (SCI) aims to capture the high-dimensional (usually 3D) images using a 2D sensor (detector) in a single snapshot. Though enjoying the advantages of low-bandwidth, low-power and low-cost, applying SCI to large-scale problems (HD or UHD videos) in our daily life is still challenging. The bottleneck lies in the reconstruction algorithms; they are either too slow (iterative optimization algorithms) or not flexible to the encoding process (deep learning based end-to-end networks). In this paper, we develop fast and flexible algorithms for SCI based on the plug-and-play (PnP) framework. In addition to the widely used PnP-ADMM method, we further propose the PnP-GAP (generalized alternating projection) algorithm with a lower computational workload and prove the convergence of PnP-GAP under the SCI hardware constraints. By employing deep denoising priors, we first time show that PnP can recover a UHD color video ($3840times 1644times 48$ with PNSR above 30dB) from a snapshot 2D measurement. Extensive results on both simulation and real datasets verify the superiority of our proposed algorithm. The code is available at https://github.com/liuyang12/PnP-SCI.
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