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Register a new userMulti-Domain Adaptation in Brain MRI through Paired Consistency and Adversarial Learning
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Supervised learning algorithms trained on medical images will often fail to generalize across changes in acquisition parameters. Recent work in domain adaptation addresses this challenge and successfully leverages labeled data in a source domain to perform well on an unlabeled target domain. Inspired by recent work in semi-supervised learning we introduce a novel method to adapt from one source domain to $n$ target domains (as long as there is paired data covering all domains). Our multi-domain adaptation method utilises a consistency loss combined with adversarial learning. We provide results on white matter lesion hyperintensity segmentation from brain MRIs using the MICCAI 2017 challenge data as the source domain and two target domains. The proposed method significantly outperforms other domain adaptation baselines.
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Left ventricle segmentation and morphological assessment are essential for improving diagnosis and our understanding of cardiomyopathy, which in turn is imperative for reducing risk of myocardial infarctions in patients. Convolutional neural network (CNN) based methods for cardiac magnetic resonance (CMR) image segmentation rely on supervision with pixel-level annotations, and may not generalize well to images from a different domain. These methods are typically sensitive to variations in imaging protocols and data acquisition. Since annotating multi-sequence CMR images is tedious and subject to inter- and intra-observer variations, developing methods that can automatically adapt from one domain to the target domain is of great interest. In this paper, we propose an approach for domain adaptation in multi-sequence CMR segmentation task using transfer learning that combines multi-source image information. We first train an encoder-decoder CNN on T2-weighted and balanced-Steady State Free Precession (bSSFP) MR images with pixel-level annotation and fine-tune the same network with a limited number of Late Gadolinium Enhanced-MR (LGE-MR) subjects, to adapt the domain features. The domain-adapted network was trained with just four LGE-MR training samples and obtained an average Dice score of $sim$85.0% on the test set comprises of 40 LGE-MR subjects. The proposed method significantly outperformed a network without adaptation trained from scratch on the same set of LGE-MR training data.
Fetal brain MRI is useful for diagnosing brain abnormalities but is challenged by fetal motion. The current protocol for T2-weighted fetal brain MRI is not robust to motion so image volumes are degraded by inter- and intra- slice motion artifacts. Besides, manual annotation for fetal MR image quality assessment are usually time-consuming. Therefore, in this work, a semi-supervised deep learning method that detects slices with artifacts during the brain volume scan is proposed. Our method is based on the mean teacher model, where we not only enforce consistency between student and teacher models on the whole image, but also adopt an ROI consistency loss to guide the network to focus on the brain region. The proposed method is evaluated on a fetal brain MR dataset with 11,223 labeled images and more than 200,000 unlabeled images. Results show that compared with supervised learning, the proposed method can improve model accuracy by about 6% and outperform other state-of-the-art semi-supervised learning methods. The proposed method is also implemented and evaluated on an MR scanner, which demonstrates the feasibility of online image quality assessment and image reacquisition during fetal MR scans.
Recently unsupervised domain adaptation for the semantic segmentation task has become more and more popular due to high-cost of pixel-level annotation on real-world images. However, most domain adaptation methods are only restricted to single-source-single-target pair, and can not be directly extended to multiple target domains. In this work, we propose a collaborative learning framework to achieve unsupervised multi-target domain adaptation. An unsupervised domain adaptation expert model is first trained for each source-target pair and is further encouraged to collaborate with each other through a bridge built between different target domains. These expert models are further improved by adding the regularization of making the consistent pixel-wise prediction for each sample with the same structured context. To obtain a single model that works across multiple target domains, we propose to simultaneously learn a student model which is trained to not only imitate the output of each expert on the corresponding target domain, but also to pull different expert close to each other with regularization on their weights. Extensive experiments demonstrate that the proposed method can effectively exploit rich structured information contained in both labeled source domain and multiple unlabeled target domains. Not only does it perform well across multiple target domains but also performs favorably against state-of-the-art unsupervised domain adaptation methods specially trained on a single source-target pair
Automatic and accurate segmentation of the ventricles and myocardium from multi-sequence cardiac MRI (CMR) is crucial for the diagnosis and treatment management for patients suffering from myocardial infarction (MI). However, due to the existence of domain shift among different modalities of datasets, the performance of deep neural networks drops significantly when the training and testing datasets are distinct. In this paper, we propose an unsupervised domain alignment method to explicitly alleviate the domain shifts among different modalities of CMR sequences, emph{e.g.,} bSSFP, LGE, and T2-weighted. Our segmentation network is attention U-Net with pyramid pooling module, where multi-level feature space and output space adversarial learning are proposed to transfer discriminative domain knowledge across different datasets. Moreover, we further introduce a group-wise feature recalibration module to enforce the fine-grained semantic-level feature alignment that matching features from different networks but with the same class label. We evaluate our method on the multi-sequence cardiac MR Segmentation Challenge 2019 datasets, which contain three different modalities of MRI sequences. Extensive experimental results show that the proposed methods can obtain significant segmentation improvements compared with the baseline models.
Learning-based approaches to robotic manipulation are limited by the scalability of data collection and accessibility of labels. In this paper, we present a multi-task domain adaptation framework for instance grasping in cluttered scenes by utilizing simulated robot experiments. Our neural network takes monocular RGB images and the instance segmentation mask of a specified target object as inputs, and predicts the probability of successfully grasping the specified object for each candidate motor command. The proposed transfer learning framework trains a model for instance grasping in simulation and uses a domain-adversarial loss to transfer the trained model to real robots using indiscriminate grasping data, which is available both in simulation and the real world. We evaluate our model in real-world robot experiments, comparing it with alternative model architectures as well as an indiscriminate grasping baseline.
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