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Register a new userAuto-Classification of Retinal Diseases in the Limit of Sparse Data Using a Two-Streams Machine Learning Model
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Added by
C. H. Huck Yang
Publication date
2018
fields
Informatics Engineering
and research's language is
English
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Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main characteristics of retinal diseases, we propose a novel visual-assisted diagnosis hybrid model mixing the support vector machine (SVM) and deep neural networks (DNNs). Furthermore, we present a new clinical retina dataset, called EyeNet2, for ophthalmology incorporating 52 retina diseases classes. Using EyeNet2, our model achieves 90.43% diagnosis accuracy, and the model performance is comparable to the professional ophthalmologists.
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Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. We propose a novel visual-assisted diagnosis hybrid model based on the support vector machine (SVM) and deep neural networks (DNNs). The model incorporates complementary strengths of DNNs and SVM. Furthermore, we present a new clinical retina label collection for ophthalmology incorporating 32 retina diseases classes. Using EyeNet, our model achieves 89.73% diagnosis accuracy and the model performance is comparable to the professional ophthalmologists.
Emerging applications of machine learning in numerous areas involve continuous gathering of and learning from streams of data. Real-time incorporation of streaming data into the learned models is essential for improved inference in these applications. Further, these applications often involve data that are either inherently gathered at geographically distributed entities or that are intentionally distributed across multiple machines for memory, computational, and/or privacy reasons. Training of models in this distributed, streaming setting requires solving stochastic optimization problems in a collaborative manner over communication links between the physical entities. When the streaming data rate is high compared to the processing capabilities of compute nodes and/or the rate of the communications links, this poses a challenging question: how can one best leverage the incoming data for distributed training under constraints on computing capabilities and/or communications rate? A large body of research has emerged in recent decades to tackle this and related problems. This paper reviews recently developed methods that focus on large-scale distributed stochastic optimization in the compute- and bandwidth-limited regime, with an emphasis on convergence analysis that explicitly accounts for the mismatch between computation, communication and streaming rates. In particular, it focuses on methods that solve: (i) distributed stochastic convex problems, and (ii) distributed principal component analysis, which is a nonconvex problem with geometric structure that permits global convergence. For such methods, the paper discusses recent advances in terms of distributed algorithmic designs when faced with high-rate streaming data. Further, it reviews guarantees underlying these methods, which show there exist regimes in which systems can learn from distributed, streaming data at order-optimal rates.
In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy most of the data, while most classes have rarely few samples), which results in a challenging imbalance learning scenario. For example, there are estimated more than 40 different kinds of retinal diseases with variable morbidity, however with more than 30+ conditions are very rare from the global patient cohorts, which results in a typical long-tailed learning problem for deep learning-based screening models. In this study, we propose class subset learning by dividing the long-tailed data into multiple class subsets according to prior knowledge, such as regions and phenotype information. It enforces the model to focus on learning the subset-specific knowledge. More specifically, there are some relational classes that reside in the fixed retinal regions, or some common pathological features are observed in both the majority and minority conditions. With those subsets learnt teacher models, then we are able to distill the multiple teacher models into a unified model with weighted knowledge distillation loss. The proposed framework proved to be effective for the long-tailed retinal diseases recognition task. The experimental results on two different datasets demonstrate that our method is flexible and can be easily plugged into many other state-of-the-art techniques with significant improvements.
Agriculture is an essential industry in the both society and economy of a country. However, the pests and diseases cause a great amount of reduction in agricultural production while there is not sufficient guidance for farmers to avoid this disaster. To address this problem, we apply CNNs to plant disease recognition by building a classification model. Within the dataset of 3,642 images of apple leaves, We use a pre-trained image classification model Restnet34 based on a Convolutional neural network (CNN) with the Fastai framework in order to save the training time. Overall, the accuracy of classification is 93.765%.
The advancement of technology has resulted in a rapid increase in supernova (SN) discoveries. The Subaru/Hyper Suprime-Cam (HSC) transient survey, conducted from fall 2016 through spring 2017, yielded 1824 SN candidates. This gave rise to the need for fast type classification for spectroscopic follow-up and prompted us to develop a machine learning algorithm using a deep neural network (DNN) with highway layers. This machine is trained by actual observed cadence and filter combinations such that we can directly input the observed data array into the machine without any interpretation. We tested our model with a dataset from the LSST classification challenge (Deep Drilling Field). Our classifier scores an area under the curve (AUC) of 0.996 for binary classification (SN Ia or non-SN Ia) and 95.3% accuracy for three-class classification (SN Ia, SN Ibc, or SN II). Application of our binary classification to HSC transient data yields an AUC score of 0.925. With two weeks of HSC data since the first detection, this classifier achieves 78.1% accuracy for binary classification, and the accuracy increases to 84.2% with the full dataset. This paper discusses the potential use of machine learning for SN type classification purposes.
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