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Register a new userTraining Medical Image Analysis Systems like Radiologists
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Added by
Gabriel Maicas
Publication date
2018
fields
Informatics Engineering
and research's language is
English
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The training of medical image analysis systems using machine learning approaches follows a common script: collect and annotate a large dataset, train the classifier on the training set, and test it on a hold-out test set. This process bears no direct resemblance with radiologist training, which is based on solving a series of tasks of increasing difficulty, where each task involves the use of significantly smaller datasets than those used in machine learning. In this paper, we propose a novel training approach inspired by how radiologists are trained. In particular, we explore the use of meta-training that models a classifier based on a series of tasks. Tasks are selected using teacher-student curriculum learning, where each task consists of simple classification problems containing small training sets. We hypothesize that our proposed meta-training approach can be used to pre-train medical image analysis models. This hypothesis is tested on the automatic breast screening classification from DCE-MRI trained with weakly labeled datasets. The classification performance achieved by our approach is shown to be the best in the field for that application, compared to state of art baseline approaches: DenseNet, multiple instance learning and multi-task learning.
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The use of Deep Learning in the medical field is hindered by the lack of interpretability. Case-based interpretability strategies can provide intuitive explanations for deep learning models decisions, thus, enhancing trust. However, the resulting explanations threaten patient privacy, motivating the development of privacy-preserving methods compatible with the specifics of medical data. In this work, we analyze existing privacy-preserving methods and their respective capacity to anonymize medical data while preserving disease-related semantic features. We find that the PPRL-VGAN deep learning method was the best at preserving the disease-related semantic features while guaranteeing a high level of privacy among the compared state-of-the-art methods. Nevertheless, we emphasize the need to improve privacy-preserving methods for medical imaging, as we identified relevant drawbacks in all existing privacy-preserving approaches.
Medical image analysis typically includes several tasks such as enhancement, segmentation, and classification. Traditionally, these tasks are implemented using separate deep learning models for separate tasks, which is not efficient because it involves unnecessary training repetitions, demands greater computational resources, and requires a relatively large amount of labeled data. In this paper, we propose a multi-task training approach for medical image analysis, where individual tasks are fine-tuned simultaneously through relevant knowledge transfer using a unified modality-specific feature representation (UMS-Rep). We explore different fine-tuning strategies to demonstrate the impact of the strategy on the performance of target medical image tasks. We experiment with different visual tasks (e.g., image denoising, segmentation, and classification) to highlight the advantages offered with our approach for two imaging modalities, chest X-ray and Doppler echocardiography. Our results demonstrate that the proposed approach reduces the overall demand for computational resources and improves target task generalization and performance. Further, our results prove that the performance of target tasks in medical images is highly influenced by the utilized fine-tuning strategy.
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