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Register a new userThe Flux Limited Keller-Segel System; Properties and Derivation from Kinetic Equations
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Beno^it Perthame
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The flux limited Keller-Segel (FLKS) system is a macroscopic model describing bacteria motion by chemotaxis which takes into account saturation of the velocity. The hyper-bolic form and some special parabolic forms have been derived from kinetic equations describing the run and tumble process for bacterial motion. The FLKS model also has the advantage that traveling pulse solutions exist as observed experimentally. It has attracted the attention of many authors recently. We design and prove a general derivation of the FLKS departing from a kinetic model under stiffness assumption of the chemotactic response and rescaling the kinetic equation according to this stiffness parameter. Unlike the classical Keller-Segel system, solutions of the FLKS system do not blow-up in finite or infinite time. Then we investigate the existence of radially symmetric steady state and long time behaviour of this flux limited Keller-Segel system.
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We study the regularity and large-time behavior of a crowd of species driven by chemo-tactic interactions. What distinguishes the different species is the way they interact with the rest of the crowd: the collective motion is driven by different chemical reactions which end up in a coupled system of parabolic Patlak-Keller-Segel equations. We show that the densities of the different species diffuse to zero provided the chemical interactions between the different species satisfy certain sub-critical condition; the latter is intimately related to a log-Hardy-Littlewood-Sobolev inequality for systems due to Shafrir & Wolansky. Thus for example, when two species interact, one of which has mass less than $4pi$, then the 2-system stays smooth for all time independent of the total mass of the system, in sharp contrast with the well-known breakdown of one specie with initial mass$> 8pi$.
Perhaps the most classical diffusion model for chemotaxis is the Patlak-Keller-Segel system begin{equation} label{ks0} left{ begin{aligned} u_t =& Delta u - abla cdot(u abla v) quad inn R^2times(0,infty), v =& (-Delta_{R^2})^{-1} u := frac 1{2pi} int_{R^2} , log frac 1{|x-z|} u(z,t), dz, & qquad u(cdot ,0) = u_0 ge 0quadhbox{in } R^2. end{aligned} right. end{equation} We consider the {em critical mass case} $int_{R^2} u_0(x), dx = 8pi$ which corresponds to the exact threshold between finite-time blow-up and self-similar diffusion towards zero. We find a radial function $u_0^*$ with mass $8pi$ such that for any initial condition $u_0$ sufficiently close to $u_0^*$ the solution $u(x,t)$ of equ{ks0} is globally defined and blows-up in infinite time. As $tto+infty $ it has the approximate profile $$ u(x,t) approx frac 1{la^2} U_0left (frac {x-xi(t)}{la(t)} right ), quad U_0(y)= frac{8}{(1+|y|^2)^2}, $$ where $la(t) approx frac c{sqrt{log t}}, xi(t)to q $ for some $c>0$ and $qin R^2$
We exploit the existence and nonlinear stability of boundary spike/layer solutions of the Keller-Segel system with logarithmic singular sensitivity in the half space, where the physical zero-flux and Dirichlet boundary conditions are prescribed. We first prove that, under above boundary conditions, the Keller-Segel system admits a unique boundary spike-layer steady state where the first solution component (bacterial density) of the system concentrates at the boundary as a Dirac mass and the second solution component (chemical concentration) forms a boundary layer profile near the boundary as the chemical diffusion coefficient tends to zero. Then we show that this boundary spike-layer steady state is asymptotically nonlinearly stable under appropriate perturbations. As far as we know, this is the first result obtained on the global well-posedness of the singular Keller-Segel system with nonlinear consumption rate. We introduce a novel strategy of relegating the singularity, via a Cole-Hopf type transformation, to a nonlinear nonlocality which is resolved by the technique of taking antiderivatives, i.e. working at the level of the distribution function. Then, we carefully choose weight functions to prove our main results by suitable weighted energy estimates with Hardys inequality that fully captures the dissipative structure of the system.
Based on some elementary estimates for the space-time derivatives of the heat kernel, we use a bootstrapping approach to establish the optimal decay rates for the $L^q(mathbb{R}^d)$ ($1leq qleqinfty$, $dinmathbb{N}$) norm of the space-time derivatives of solutions to the (modified) Patlak-Keller-Segel equations with initial data in $L^1(mathbb{R}^d)$, which implies the joint space-time analyticity of solutions. When the $L^1(mathbb{R}^d)$ norm of the initial datum is small, the upper bound for the decay estimates is global in time, which yields a lower bound on the growth rate of the radius of space-time analyticity in time. As a byproduct, the space analyticity is obtained for any initial data in $L^1(mathbb{R}^d)$. The decay estimates and space-time analyticity are also established for solutions bounded in both space and time variables. The results can be extended to a more general class of equations, including the Navier-Stokes equations.
In this paper, we proposed a coupled Patlak-Keller-Segel-Navier-Stokes system, which has dissipative free energy. On the plane $rr^2$, if the total mass of the cells is strictly less than $8pi$, classical solutions exist for any finite time, and their $H^s$-Sobolev norms are almost uniformly bounded in time. For the radially symmetric solutions, this $8pi$-mass threshold is critical. On the torus $mathbb{T}^2$, the solutions are uniformly bounded in time under the same mass constraint.
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