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Fuzzy Statistical Matrices for Cell Classification

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 Added by Guillaume Thibault
 Publication date 2016
and research's language is English




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In this paper, we generalize image (texture) statistical descriptors and propose algorithms that improve their efficacy. Recently, a new method showed how the popular Co-Occurrence Matrix (COM) can be modified into a fuzzy version (FCOM) which is more effective and robust to noise. Here, we introduce new fuz



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Convolutional operations have two limitations: (1) do not explicitly model where to focus as the same filter is applied to all the positions, and (2) are unsuitable for modeling long-range dependencies as they only operate on a small neighborhood. While both limitations can be alleviated by attention operations, many design choices remain to be determined to use attention, especially when applying attention to videos. Towards a principled way of applying attention to videos, we address the task of spatiotemporal attention cell search. We propose a novel search space for spatiotemporal attention cells, which allows the search algorithm to flexibly explore various design choices in the cell. The discovered attention cells can be seamlessly inserted into existing backbone networks, e.g., I3D or S3D, and improve video classification accuracy by more than 2% on both Kinetics-600 and MiT datasets. The discovered attention cells outperform non-local blocks on both datasets, and demonstrate strong generalization across different modalities, backbones, and datasets. Inserting our attention cells into I3D-R50 yields state-of-the-art performance on both datasets.
In this paper, the interval-valued intuitionistic fuzzy matrix (IVIFM) is introduced. The interval-valued intuitionistic fuzzy determinant is also defined. Some fundamental operations are also presented. The need of IVIFM is explain by an example.
Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works focus on creating hand-engineered features from these images or learn such features with deep neural networks in a fully or weakly-supervised framework. Both require prior knowledge or labelled datasets. Therefore, subsequent works propose unsupervised approaches based on generative models to learn these representations. Recently, representations learned with self-supervised contrastive loss-based methods have yielded state-of-the-art results on various imaging tasks compared to earlier unsupervised approaches. In this work, we leverage a contrastive learning framework to learn appropriate representations from single-cell fluorescent microscopy images for the task of Mechanism-of-Action classification. The proposed work is evaluated on the annotated BBBC021 dataset, and we obtain state-of-the-art results in NSC, NCSB and drop metrics for an unsupervised approach. We observe an improvement of 10% in NCSB accuracy and 11% in NSC-NSCB drop over the previously best unsupervised method. Moreover, the performance of our unsupervised approach ties with the best supervised approach. Additionally, we observe that our framework performs well even without post-processing, unlike earlier methods. With this, we conclude that one can learn robust cell representations with contrastive learning.
Machine learning has endless applications in the health care industry. White blood cell classification is one of the interesting and promising area of research. The classification of the white blood cells plays an important part in the medical diagnosis. In practise white blood cell classification is performed by the haematologist by taking a small smear of blood and careful examination under the microscope. The current procedures to identify the white blood cell subtype is more time taking and error-prone. The computer aided detection and diagnosis of the white blood cells tend to avoid the human error and reduce the time taken to classify the white blood cells. In the recent years several deep learning approaches have been developed in the context of classification of the white blood cells that are able to identify but are unable to localize the positions of white blood cells in the blood cell image. Following this, the present research proposes to utilize YOLOv3 object detection technique to localize and classify the white blood cells with bounding boxes. With exhaustive experimental analysis, the proposed work is found to detect the white blood cell with 99.2% accuracy and classify with 90% accuracy.
In this paper, a novel statistical metric learning is developed for spectral-spatial classification of the hyperspectral image. First, the standard variance of the samples of each class in each batch is used to decrease the intra-class variance within each class. Then, the distances between the means of different classes are used to penalize the inter-class variance of the training samples. Finally, the standard variance between the means of different classes is added as an additional diversity term to repulse different classes from each other. Experiments have conducted over two real-world hyperspectral image datasets and the experimental results have shown the effectiveness of the proposed statistical metric learning.
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