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Transfer entropy in continuous time, with applications to jump and neural spiking processes

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 Added by Richard Spinney
 Publication date 2016
and research's language is English




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Transfer entropy has been used to quantify the directed flow of information between source and target variables in many complex systems. While transfer entropy was originally formulated in discrete time, in this paper we provide a framework for considering transfer entropy in continuous time systems, based on Radon-Nikodym derivatives between measures of complete path realizations. To describe the information dynamics of individual path realizations, we introduce the pathwise transfer entropy, the expectation of which is the transfer entropy accumulated over a finite time interval. We demonstrate that this formalism permits an instantaneous transfer entropy rate. These properties are analogous to the behavior of physical quantities defined along paths such as work and heat. We use this approach to produce an explicit form for the transfer entropy for pure jump processes, and highlight the simplified form in the specific case of point processes (frequently used in neuroscience to model neural spike trains). Finally, we present two synthetic spiking neuron model examples to exhibit the pertinent features of our formalism, namely, that the information flow for point processes consists of discontinuous jump contributions (at spikes in the target) interrupting a continuously varying contribution (relating to waiting times between target spikes). Numerical schemes based on our formalism promise significant benefits over existing strategies based on discrete time formalisms.



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The characterisation of information processing is an important task in complex systems science. Information dynamics is a quantitative methodology for modelling the intrinsic information processing conducted by a process represented as a time series, but to date has only been formulated in discrete time. Building on previous work which demonstrated how to formulate transfer entropy in continuous time, we give a total account of information processing in this setting, incorporating information storage. We find that a convergent rate of predictive capacity, comprised of the transfer entropy and active information storage, does not exist, arising through divergent rates of active information storage. We identify that active information storage can be decomposed into two separate quantities that characterise predictive capacity stored in a process: active memory utilisation and instantaneous predictive capacity. The latter involves prediction related to path regularity and so solely inherits the divergent properties of the active information storage, whilst the former permits definitions of pathwise and rate quantities. We formulate measures of memory utilisation for jump and neural spiking processes and illustrate measures of information processing in synthetic neural spiking models and coupled Ornstein-Uhlenbeck models. The application to synthetic neural spiking models demonstrates that active memory utilisation for point processes consists of discontinuous jump contributions (at spikes) interrupting a continuously varying contribution (relating to waiting times between spikes), complementing the behaviour previously demonstrated for transfer entropy in these processes.
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