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On a lower bound for sorting signed permutations by reversals

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 Added by Ricky Xiaofeng Chen
 Publication date 2016
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and research's language is English




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Computing the reversal distances of signed permutations is an important topic in Bioinformatics. Recently, a new lower bound for the reversal distance was obtained via the plane permutation framework. This lower bound appears different from the existing lower bound obtained by Bafna and Pevzner through breakpoint graphs. In this paper, we prove that the two lower bounds are equal. Moreover, we confirm a related conjecture on skew-symmetric plane permutations, which can be restated as follows: let $p=(0,-1,-2,ldots -n,n,n-1,ldots 1)$ and let $$ tilde{s}=(0,a_1,a_2,ldots a_n,-a_n,-a_{n-1},ldots -a_1) $$ be any long cycle on the set ${-n,-n+1,ldots 0,1,ldots n}$. Then, $n$ and $a_n$ are always in the same cycle of the product $ptilde{s}$. Furthermore, we show the new lower bound via plane permutations can be interpreted as the topological genera of orientable surfaces associated to signed permutations.



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In this paper we present a simple framework to study various distance problems of permutations, including the transposition and block-interchange distance of permutations as well as the reversal distance of signed permutations. These problems are very important in the study of the evolution of genomes. We give a general formulation for lower bounds of the transposition and block-interchange distance from which the existing lower bounds obtained by Bafna and Pevzner, and Christie can be easily derived. As to the reversal distance of signed permutations, we translate it into a block-interchange distance problem of permutations so that we obtain a new lower bound. Furthermore, studying distance problems via our framework motivates several interesting combinatorial problems related to product of permutations, some of which are studied in this paper as well.
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