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Register a new userRigorous results for a population model with selection I: evolution of the fitness distribution
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Jason Schweinsberg
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We consider a model of a population of fixed size $N$ undergoing selection. Each individual acquires beneficial mutations at rate $mu_N$, and each beneficial mutation increases the individuals fitness by $s_N$. Each individual dies at rate one, and when a death occurs, an individual is chosen with probability proportional to the individuals fitness to give birth. Under certain conditions on the parameters $mu_N$ and $s_N$, we obtain rigorous results for the rate at which mutations accumulate in the population and the distribution of the fitnesses of individuals in the population at a given time. Our results confirm predictions of Desai and Fisher (2007).
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We consider a model of a population of fixed size $N$ undergoing selection. Each individual acquires beneficial mutations at rate $mu_N$, and each beneficial mutation increases the individuals fitness by $s_N$. Each individual dies at rate one, and when a death occurs, an individual is chosen with probability proportional to the individuals fitness to give birth. Under certain conditions on the parameters $mu_N$ and $s_N$, we show that the genealogy of the population can be described by the Bolthausen-Sznitman coalescent. This result confirms predictions of Desai, Walczak, and Fisher (2013), and Neher and Hallatschek (2013).
We generalize the evolution model introduced by Guiol, Machado and Schinazi (2010). In our model at odd times a random number X of species is created. Each species is endowed with a random fitness with arbitrary distribution on $[0, 1]$. At even times a random number Y of species is removed, killing the species with lower fitness. We show that there is a critical fitness $f_c$ below which the number of species hits zero i.o. and above of which this number goes to infinity. We prove uniform convergence for the distribution of surviving species and describe the phenomena which could not be observed in previous works with uniformly distributed fitness.
We derive and apply a partial differential equation for the moment generating function of the Wright-Fisher model of population genetics.
We propose a new mechanism leading to scale-free networks which is based on the presence of an intrinsic character of a vertex called fitness. In our model, a vertex $i$ is assigned a fitness $x_i$, drawn from a given probability distribution function $f(x)$. During network evolution, with rate $p$ we add a vertex $j$ of fitness $x_j$ and connect to an existing vertex $i$ of fitness $x_i$ selected preferentially to a linking probability function $g(x_i,x_j)$ which depends on the fitnesses of the two vertices involved and, with rate $1-p$ we create an edge between two already existed vertices with fitnesses $x_i$ and $x_j$, with a probability also preferential to the connection function $g(x_i,x_j)$. For the proper choice of $g$, the resulting networks have generalized power laws, irrespective of the fitness distribution of vertices.
Preferential attachment models form a popular class of growing networks, where incoming vertices are preferably connected to vertices with high degree. We consider a variant of this process, where vertices are equipped with a random initial fitness representing initial inhomogeneities among vertices and the fitness influences the attractiveness of a vertex in an additive way. We consider a heavy-tailed fitness distribution and show that the model exhibits a phase transition depending on the tail exponent of the fitness distribution. In the weak disorder regime, one of the old vertices has maximal degree irrespective of fitness, while for strong disorder the vertex with maximal degree has to satisfy the right balance between fitness and age. Our methods use martingale methods to show concentration of degree evolutions as well as extreme value theory to control the fitness landscape.
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