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(abridged) Infrared selection is a potentially powerful way to identify heavily obscured AGN missed in even the deepest X-ray surveys. Using a 24 micron-selected sample in GOODS-S, we test the reliability and completeness of three infrared AGN selection methods: (1) IRAC color-color selection, (2) IRAC power-law selection, and (3) IR-excess selection; we also evaluate a number of infrared excess approaches. We find that the vast majority of non-power-law IRAC color-selected AGN candidates in GOODS-S have colors consistent with those of star-forming galaxies. Contamination by star-forming galaxies is most prevalent at low 24 micron flux densities (~100 uJy) and high redshifts (z~2), but the fraction of potential contaminants is still high (~50%) at 500 uJy, the highest flux density probed reliably by our survey. AGN candidates selected via a simple, physically-motivated power-law criterion (PLGs), however, appear to be reliable. We confirm that the infrared excess methods successfully identify a number of AGN, but we also find that such samples may be significantly contaminated by star-forming galaxies. Adding only the secure Spitzer-selected PLG, color-selected, IR-excess, and radio/IR-selected AGN candidates to the deepest X-ray-selected AGN samples directly increases the number of known X-ray AGN (84) by 54-77%, and implies an increase to the number of 24 micron-detected AGN of 71-94%. Finally, we show that the fraction of MIR sources dominated by an AGN decreases with decreasing MIR flux density, but only down to f_24 = 300 uJy. Below this limit, the AGN fraction levels out, indicating that a non-negligible fraction (~10%) of faint 24 micron sources (the majority of which are missed in the X-ray) are powered not by star formation, but by the central engine.
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We provide constraints on the AGN contribution to the mid-IR extragalactic background light from a correlation analysis of deep X-ray and mid-IR observations in two regions centred on the Lockman Hole (LH) and Hubble Deep Field North (HDFN). Among the 76 galaxies detected by XMM in the LH area (200 square arcminutes), 24 show mid-IR emission, but the relative percentage of X-ray sources with mid-IR counterparts increases with the band energy: from 30% of the 0.5-2 keV sources up to 63% of the 5-10 keV sources. In contrast, only a small fraction of the mid-IR sources (around 10%) show X-ray emission. In the region centred on the HDFN (24 square arcminutes), 25% of the mid-IR sources are detected in the X-ray, while 30-40% of the X-ray sources show mid-IR emission. Under the conservative assumption that all XMM sources are AGN-dominated, AGNs contribute 15% of the total mid-IR flux in the LH. For the HDFN we have assumed that AGN-dominated sources are luminous X-ray sources with radio to X-ray SEDs typical of local AGNs, in which case we find that 18% of the mid-IR flux are due to AGN emission. If we put together all the existing information from the deepest HDFN data to the shallow large-area BeppoSAX observations in the ELAIS S1 region using the median mid-IR to X-ray spectral indices as a function of the X-ray flux, we find an AGN contribution to the 15um background of 17%. We conclude that the population of IR luminous galaxies detected in the ISOCAM deep surveys are mainly constituted by dust-obscured starbursts.
Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner. Cell synchronization techniques have been generally employed to minimize the variation in cell cycle position. However, synchronization techniques are cumbersome and imprecise and the agents used to synchronize the cells potentially have other unknown effects on the cells. An alternative approach is to determine the age structure in the population and account for the cell cycle positional effects post hoc. Here we provide a formalism to use quantifiable age distributions from live cell microscopy experiments to parameterize an age-structured model of cell population response.
We present measurements of the specific ultraviolet luminosity density from a sample of 483 galaxies at 6<z<8. These galaxies were selected from new deep near-infrared HST imaging from the CANDELS, HUDF09 and ERS programs. In contrast to the majority of previous analyses, which assume that the distribution of galaxy ultraviolet (UV) luminosities follows a Schechter distribution, and that the distribution continues to luminosities far below our observable limit, we investigate the contribution to reionization from galaxies which we can observe, free from these assumptions. We find that the observable population of galaxies can sustain a fully reionized IGM at z=6, if the average ionizing photon escape fraction (f_esc) is ~30%. A number of previous studies have measured UV luminosity densities at these redshifts that vary by 5X, with many concluding that galaxies could not complete reionization by z=6 unless a large population of galaxies fainter than the detection limit were invoked, or extremely high values of f_esc were present. The observed UV luminosity density from our observed galaxy samples at z=7-8 is not sufficient to maintain a fully reionized IGM unless f_esc>50%. Combining our observations with constraints on the emission rate of ionizing photons from Ly-alpha forest observations at z=6, we can constrain f_esc<34% (2-sigma) if the observed galaxies are the only contributors to reionization, or <13% (2-sigma) if the luminosity function extends to M_UV = -13. These escape fractions are sufficient to complete reionization by z=6. These constraints imply that the volume ionized fraction of the IGM becomes less than unity at z>7, consistent with a number of complementary reionization probes. If faint galaxies dominate reionization, future JWST observations will probe deep enough to see them, providing an indirect constraint on the ionizing photon escape fraction [abridged].
The cosmic history of supermassive black hole (SMBH) growth is important for understanding galaxy evolution, reionization and the physics of accretion. Recent NuSTAR, Swift-BAT and textit{Chandra} hard X-ray surveys have provided new constraints on the space density of heavily obscured Active Galactic Nuclei (AGN). Using the new X-ray luminosity function derived from these data, we here estimate the accretion efficiency of SMBHs and their contribution to reionization. We calculate the total ionizing radiation from active galactic nuclei (AGN) as a function of redshift, based on the X radiation and distribution of obscuring column density, converted to UV wavelengths. Limiting the luminosity function to unobscured AGN only, our results agree with current UV luminosity functions of unobscured AGN. For realistic assumptions about the escape fraction, the contribution of all AGN to cosmic reionization is $sim4$ times lower than the galaxy contribution (23% at $zsim6$). Our results also offer an observationally constrained prescription that can be used in simulations or models of galaxy evolution. To estimate the average efficiency with which supermassive black holes convert mass to light, we compare the total radiated energy, converted from X-ray light using a bolometric correction, to the most recent local black hole mass density. The most likely value, $eta sim 0.3-0.34$, approaches the theoretical limit for a maximally rotating Kerr black hole, $eta=0.42$, implying that on average growing supermassive black holes are spinning rapidly.
Recent dynamical analyses suggest that some Jupiter family comets (JFCs) may originate in the main asteroid belt instead of the outer solar system. This possibility is particularly interesting given evidence that icy main-belt objects are known to be present in the Themis asteroid family. We report results from dynamical analyses specifically investigating the possibility that icy Themis family members could contribute to the observed population of JFCs. Numerical integrations show that such dynamical evolution is indeed possible via a combination of eccentricity excitation apparently driven by the nearby 2:1 mean-motion resonance with Jupiter, gravitational interactions with planets other than Jupiter, and the Yarkovsky effect. We estimate that, at any given time, there may be tens of objects from the Themis family on JFC-like orbits with the potential to mimic active JFCs from the outer solar system, although not all, or even any, may necessarily be observably active. We find that dynamically evolved Themis family objects on JFC-like orbits have semimajor axes between 3.15 au and 3.40 au for the vast majority of their time on such orbits, consistent with the strong role that the 2:1 mean-motion resonance with Jupiter likely plays in their dynamical evolution. We conclude that a contribution from the Themis family to the active JFC population is plausible, although further work is needed to better characterize this contribution.
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