Rat collagen II – induced arthritis is a model of chronic
inflammation induced by Mycobacterium butyricum and collagen II. It is
characterized by similar pathophysiological and pathobiochemical changes
as rheumatoid arthritis (RA) in humans. In th
e present study, the
biochemical and histopathological effects of vitamin E, allopurinol (Allo),
on RA of rats were investigated. The oxidative stress indices and
prostaglandin E were evaluated.
