The rapid growth in published clinical trials makes it difficult to maintain up-to-date systematic reviews, which require finding all relevant trials. This leads to policy and practice decisions based on out-of-date, incomplete, and biased subsets of
available clinical evidence. Extracting and then normalising Population, Intervention, Comparator, and Outcome (PICO) information from clinical trial articles may be an effective way to automatically assign trials to systematic reviews and avoid searching and screening---the two most time-consuming systematic review processes. We propose and test a novel approach to PICO span detection. The major difference between our proposed method and previous approaches comes from detecting spans without needing annotated span data and using only crowdsourced sentence-level annotations. Experiments on two datasets show that PICO span detection results achieve much higher results for recall when compared to fully supervised methods with PICO sentence detection at least as good as human annotations. By removing the reliance on expert annotations for span detection, this work could be used in a human-machine pipeline for turning low-quality, crowdsourced, and sentence-level PICO annotations into structured information that can be used to quickly assign trials to relevant systematic reviews.
We present a simple yet effective Targeted Adversarial Training (TAT) algorithm to improve adversarial training for natural language understanding. The key idea is to introspect current mistakes and prioritize adversarial training steps to where the
model errs the most. Experiments show that TAT can significantly improve accuracy over standard adversarial training on GLUE and attain new state-of-the-art zero-shot results on XNLI. Our code will be released upon acceptance of the paper.
Healthcare predictive analytics aids medical decision-making, diagnosis prediction and drug review analysis. Therefore, prediction accuracy is an important criteria which also necessitates robust predictive language models. However, the models using
deep learning have been proven vulnerable towards insignificantly perturbed input instances which are less likely to be misclassified by humans. Recent efforts of generating adversaries using rule-based synonyms and BERT-MLMs have been witnessed in general domain, but the ever-increasing biomedical literature poses unique challenges. We propose BBAEG (Biomedical BERT-based Adversarial Example Generation), a black-box attack algorithm for biomedical text classification, leveraging the strengths of both domain-specific synonym replacement for biomedical named entities and BERT-MLM predictions, spelling variation and number replacement. Through automatic and human evaluation on two datasets, we demonstrate that BBAEG performs stronger attack with better language fluency, semantic coherence as compared to prior work.
