An attempt was made to have a better understanding of wond healing in
skin of adult white swiss mice. The process of healing showed microscopic
changes confirmed epidermal and dermal regions. The rate of change was
rapid up to ٤٨ hours. the epithl
ium invaded actively underlying connective
tissue but still detec-table whenever vascularity in the wound had subsided to
the dermis. By the time of epidermal cell-ularity, there was a closely packed
mass of cells immediately subjacent to the epithelium, which mostly represents
predominant cell types of in the subepidermal region. Our prognostic showed
that connective tissue accompanied by many dilated capillaries. There was also
an appearance of collagen fibers laying between the cells. The epithelium
followes the boundary of living connective tissue and comes into contact with
the dermal cells. Close contact between dermal and epidermal cells happened at
the time when epithelial invasion ceased and the basement membrane was
reformed close to the epithelium.
