A product study of the reaction of some five-membered heteroaromatic
primary amines with formalin in Acetonitrile was made: Aminols of general
formula (G-NH-CH٢OH) were identified in most cases at pH (٧،٥-٩) in good
yield. Reaction of ٥-methyl ٣-A
minoisoxazol with formalin under basis media
(pH~٩) give the Aminal (G-NH-CH٢-NH-G).
