Imines based on different and secondary amines were synthesized by
reaction of acetylacetone with 2-amino-5-nitro phenol, adamantine amine, 1.7-
diamino heptane and o-aminophenol. 2.4-bis (2-hydroxy-4-nitro-1-imino
phenyl) pentane, 2.4-bis (2-imin
o admantyl) pentane, 2.4-bis(2hydrox y-1-
iminophenyl) pentane and 1.5.13.18-tetraaza- 2.4.14.16- tetramethylcyclotetracosan-
1.4.13.16-tetraene have been characterized by EA, IR, 1HNMR
and 13C-NMR.
Formaldehyde is classified by the World Health Organization (International Agency
for Research on Cancer) as a carcinogen in Group 1. The upper limit allowed for use in
cosmetic products as a preservative has to not exceed 0.2%. This study aims to
detect and
determine formaldehyde level in some cosmetic products available in the local market
using acetyl acetone method. Formaldehyde was detected in 77% of the studied cosmetic
products (49 samples) despite the fact that most of them were not labeled formaldehyde or
formaldehyde donor preservatives (about 70%). The amount of formaldehyde in keratin
samples were higher than the allowed limit (0.34% -11.73%) except one sample 0.18%. pH
decrease and temperature increase of keratin samples led to an increase of formaldehyde
level as a result of its release from preservatives.
