The study included 985 cases of Hydatidiform mole. 262 of which needed
chemotherapy due to malignant transformation or invasive mole. i.e.24.6%.
It was noticed that malignant transformation was associated clearly with group of
factors like advance
d age, low socioeconomi states, multiparity, increase of
uterine size more than gestational age, the size of the uterus, the presence of
ovarian Lutein cysts, recurrent vesicular mole, evacuation, of Hydatidiform mole
without suction, operetve interference especially laparotomy, grade of
differentiation of vescular mole.
it was also found that there is increase of malignant tranformation in thos women
who used medical barrier contraceptive methods more than those who used
hôrmonal contrceptive methods Knowing these risk factors helps in early
diagnosis and treatment of those high risk. cases and decreases the incidence of
malignant transformation.
