Coronal Mass Ejections (CMEs) drive space weather activity at Earth and throughout the solar system. Current CME-related space weather predictions rely on information reconstructed from coronagraphs, sometimes from only a single viewpoint, to drive a simple interplanetary propagation model, which only gives the arrival time or limited additional information. We present the coupling of three established models into OSPREI (Open Solar Physics Rapid Ensemble Information), a new tool that describes Sun-to-Earth CME behavior, including the location, orientation, size, shape, speed, arrival time, and internal thermal and magnetic properties, on the timescale needed for forecasts. First, ForeCAT describes the trajectory that a CME takes through the solar corona. Second, ANTEATR simulates the propagation, including expansion and deformation, of a CME in interplanetary space and determines the evolution of internal properties via conservation laws. Finally, FIDO produces in situ profiles for a CMEs interaction with a synthetic spacecraft. OSPREI includes ensemble modeling by varying each input parameter to probe any uncertainty in their values, yielding probabilities for all outputs. Standardized visualizations are automatically generated, providing easily-accessible, essential information for space weather forecasting. We show OSPREI results for a CME observed in the corona on 2021 April 22 and at Earth on 2021 April 25. We approach this CME as a forecasting proof-of-concept, using information analogous to what would be available in real time rather than fine-tuning input parameters to achieve a best fit for a detailed scientific study. The OSPREI prediction shows good agreement with the arrival time and in situ properties.
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